| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA833625 | F | Negative inotropic potency as decrease in the developed tension in isolated guinea pig left artium | Cavia porcellus | 33 | organism-based format | Scientific Literature | ||
| 2. | ALA835752 | F | Vasorelaxant activity determined by percentage inhibition of calcium-induced contraction on K+ depolarized guinea pig aortic strip at 5x10E-5 M | Cavia porcellus | 38 | organism-based format | Scientific Literature | ||
| 3. | ALA835756 | F | Negative chronotropic activity was determined as percent decrease in the artial rate in spontaneously beating guinea pig artium at 5x10E-5 M (n=6-8) | Cavia porcellus | 35 | organism-based format | Scientific Literature | ||
| 4. | ALA836517 | F | Negative inotropic activity as decrease in the developed tension in isolated guinea pig left artium at 5x10E-5 M (n=4-6) | Cavia porcellus | 29 | organism-based format | Scientific Literature | ||
| 5. | ALA1011144 | F | Antiproliferative activity against human A2780 cells after 3 days by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 6. | ALA1011145 | F | Antiproliferative activity against human A2780/DX3 cells after 3 days by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 7. | ALA1011147 | B | Reversal of P-gp 170-mediated multidrug resistance in human A2780/DX3 cells assessed as reduction in doxorubicin IC50 at IC5 pretreated for 6 hrs before doxorubicin administration measured after 3 days by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 8. | ALA1011148 | B | Reversal of P-gp 170-mediated multidrug resistance in human A2780/DX3 cells assessed as reduction in doxorubicin IC50 at IC0 pretreated for 6 hrs before doxorubicin administration measured after 3 days by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 9. | ALA1011149 | B | Reversal of P-gp 170-mediated multidrug resistance in human A2780/DX3 cells assessed as increase in intracellular doxorubicin accumulation at 5 times IC5 pretreated for 2 hrs before doxorubicin administration measured after 2 hrs by flow cytometry | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 10. | ALA1011150 | B | Reversal of P-gp 170-mediated multidrug resistance in human A2780 cells assessed as increase in intracellular doxorubicin accumulation at 5 times IC5 pretreated for 2 hrs before doxorubicin administration measured after 2 hrs by flow cytometry | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 11. | ALA1011151 | B | Reversal of P-gp 170-mediated multidrug resistance in human A2780/DX3 cells assessed as increase in intracellular doxorubicin accumulation at 5 times IC5 pretreated for 2 hrs before doxorubicin administration measured after 2 hrs by epifluorescent microscopic analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 12. | ALA1011152 | F | Down regulation of P-gp 170 expression in human A2780/DX3 cells after 72 hrs by flow cytometry | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 13. | ALA1011153 | F | Down regulation of P-gp 170 expression in human A2780 cells after 72 hrs by flow cytometry | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 14. | ALA1011162 | F | Antiproliferative activity against human A2780 cells at 2.20 uM after 3 days by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA1012058 | F | Antiproliferative activity against human A2780/DX3 cells at 2.40 uM after 3 days by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA2411795 | B | Inhibition of MDR1 in multidrug resistant human A2780/DX3 cells assessed as reduction in doxorubicin IC50 for antiproliferative activity by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 17. | ALA4423055 | A | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability up to 100 uM after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4423056 | A | Cytotoxicity against HEK293 cells assessed as reduction in cell viability up to 100 uM after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4423057 | A | Cytotoxicity against human HepG2 cells assessed as morphological alteration up to 100 uM after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4423058 | A | Cytotoxicity against HEK293 cells assessed as morphological alteration up to 100 uM after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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