# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA788870 | F | Ability to induce [3H]-5-HT release from prelabeled rat whole brain synaptosome preparations at 10e-5 M concentration | Rattus norvegicus | 5 | ALA1122159 | organism-based format | Scientific Literature | |
2. | ALA788871 | F | Ability to induce [3H]5-HT release from prelabeled rat whole brain synaptosome preparations at 10e-6 M concentration | Rattus norvegicus | 5 | ALA1122159 | organism-based format | Scientific Literature | |
3. | ALA788872 | F | Ability to induce [3H]5-HT release from prelabeled rat whole brain synaptosome preparations at 10e-7 M concentration | Rattus norvegicus | 5 | ALA1122159 | organism-based format | Scientific Literature | |
4. | ALA792039 | F | Compound was tested for hallucinogenic activity in rats at 0.69 dose(mg/kg); Number of rats selecting the LSD lever/ number of rats responding (4/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
5. | ALA792851 | F | Compound was tested for hallucinogenic activity in rats at 1.82 dose (mg/kg); 0/0, highest dose tested | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
6. | ALA792878 | F | Compound was tested for hallucinogenic activity in rats at dose 1.38(mg/kg); Number of rats selecting the LSD lever/ number of rats responding (4/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
7. | ALA792879 | F | Compound was tested for hallucinogenic activity in rats at dose 1.72 (mg/kg); Number of rats selecting the LSD lever/ number of rats responding (4/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
8. | ALA792890 | F | Compound was tested for hallucinogenic activity in rats at the dose 0.17(mg/kg); Number of rats selecting the LSD lever/ number of rats responding 23/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
9. | ALA792896 | F | Compound was tested for hallucinogenic activity in rats at the dose 0.34(mg/kg); Number of rats selecting the LSD lever/ number of rats responding (2/8) | Rattus norvegicus | 2 | ALA1123242 | organism-based format | Scientific Literature | |
10. | ALA883673 | A | Michaelis-Menten constant for oxidation to 3,4-OH-MA by cytochrome P450 2D6 (wild type pSP19T7LT) | Homo sapiens | 5 | ALA1141093 | single protein format | Scientific Literature | |
11. | ALA883679 | A | Vmax for oxidation to 3,4-OH-MA by cytochrome P450 2D6 (wild type pSP19T7LT); expressed in 10E5 fluorescence units min-1 nmol-1 CYP | Homo sapiens | 5 | ALA1141093 | assay format | Scientific Literature | |
12. | ALA872251 | A | Michaelis-Menten constant for oxidation to MDA by cytochrome P450 2D6 (Phe120Ala mutant) | Homo sapiens | 5 | ALA1141093 | single protein format | Scientific Literature | |
13. | ALA872252 | A | Michaelis-Menten constant for oxidation to 3,4-OH-MA by cytochrome P450 2D6 (Phe120Ala mutant) | Homo sapiens | 5 | ALA1141093 | single protein format | Scientific Literature | |
14. | ALA873567 | A | Michaelis-Menten constant for oxidation to N-OH-MDMA by cytochrome P450 2D6 (Phe120Ala mutant) | Homo sapiens | 5 | ALA1141093 | single protein format | Scientific Literature | |
15. | ALA873573 | A | Vmax for oxidation to MDA by cytochrome P450 2D6 (Phe120Ala mutant) | Homo sapiens | 5 | ALA1141093 | single protein format | Scientific Literature | |
16. | ALA873575 | A | Vmax for oxidation to N-OH-MDMA by cytochrome P450 2D6 (Phe120Ala mutant); expressed in 10E5 fluorescence units min-1 nmol-1 CYP | Homo sapiens | 5 | ALA1141093 | assay format | Scientific Literature | |
17. | ALA873576 | A | Vmax for oxidation to 3,4-OH-MA by cytochrome P450 2D6 (Phe120Ala mutant); expressed as 10E5 fluorescence units min-1 nmol-1 CYP; expressed in 10E5 fluorescence units min-1 nmol-1 CYP | Homo sapiens | 1 | ALA1141093 | assay format | Scientific Literature | |
18. | ALA1930561 | F | Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assay | Homo sapiens | 19 | ALA1926662 | cell-based format | Scientific Literature | |
19. | ALA1930650 | F | Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate reader | Macaca mulatta | 20 | ALA1926662 | cell-based format | Scientific Literature | |
20. | ALA1930659 | F | Activation of human TAAR1 expressed in human HEK293T cells assessed as cAMP accumulation after 10 mins by BRET assay | Homo sapiens | 4 | ALA1926662 | cell-based format | Scientific Literature |