# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA884690 | B | Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C with the compound dissolved in DMSO | Homo sapiens | 7 | ALA1141075 | single protein format | Scientific Literature | |
2. | ALA883910 | B | Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 degrees C | Human betaherpesvirus 5 | 24 | ALA1141075 | single protein format | Scientific Literature | |
3. | ALA872297 | B | Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 degrees C | Human alphaherpesvirus 3 | 6 | ALA1141075 | single protein format | Scientific Literature | |
4. | ALA872302 | B | Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 degrees C | Human alphaherpesvirus 1 | 6 | ALA1141075 | single protein format | Scientific Literature | |
5. | ALA885295 | B | Inhibition of human gamma DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C; nd is not determined | Homo sapiens | 1 | ALA1141075 | single protein format | Scientific Literature | |
6. | ALA884194 | F | Antiviral activity against human cytomegalovirus (Davis strain) grown on human foreskin fibroblast cells determined by reduction in plaque formation upon incubation at 37 degrees C with the compound dissolved in DMSO | Homo sapiens | 17 | ALA1141075 | cell-based format | Scientific Literature | |
7. | ALA884195 | F | Antiviral activity against Varicella-Zoster virus (Webster strain) grown on human foreskin fibroblast cells determined by vedduction in plaque formation upon incubation at 37 degrees C with the compound dissolved in DMSO until plaque were formed | Homo sapiens | 4 | ALA1141075 | cell-based format | Scientific Literature | |
8. | ALA884196 | F | Antiviral activity against herpes simplex virus type 1 (KOS strain) grown on human foreskin fibroblast cells determined by vedduction in plaque formation upon incubation at 37 degrees C with the compound dissolved in DMSO until plaque were formed | Homo sapiens | 4 | ALA1141075 | cell-based format | Scientific Literature | |
9. | ALA872243 | T | Toxicity on uninfected human foreskin fibroblast cells determined in microscopic evaluation and quantitative neutral red dye uptake assay | Homo sapiens | 6 | ALA1141075 | cell-based format | Scientific Literature | |
10. | ALA872244 | T | Toxicity on uninfected African green monkey kidney cells determined in microscopic evaluation and quantitative neutral red dye uptake assay | Chlorocebus sabaeus | 6 | ALA1141075 | cell-based format | Scientific Literature | |
11. | ALA1116836 | B | Inhibition of HCMV recombinant DNA polymerase expressed in baculovirus infected SF9 cells after 12 mins by scintillation proximity assay | Human betaherpesvirus 5 | 34 | ALA1155400 | cell-based format | Scientific Literature | |
12. | ALA1116837 | F | Antiviral activity against Human cytomegalovirus infected in HFF cells by plaque reduction assay | Human betaherpesvirus 5 | 33 | ALA1155400 | organism-based format | Scientific Literature |