# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA880254 | Binding | Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coli | Trypanosoma brucei | 81 | ALA1141094 | assay format | Scientific Literature | |
2. | ALA865780 | Binding | Inhibitory activity against Trypanosoma cruzi hexokinase | Trypanosoma cruzi | 42 | ALA1148603 | single protein format | Scientific Literature | |
3. | ALA863956 | Functional | Cytotoxicity in human nasopharyngeal carcinoma KB cell line | Homo sapiens | 32 | ALA1148603 | cell-based format | Scientific Literature | |
4. | ALA865754 | ADME | Therapeutic index TI=LD50(KB)/IC50(TcHK) | 32 | ALA1148603 | assay format | Scientific Literature | ||
5. | ALA865755 | Functional | Cytotoxicity to Dictyostelium discoideum | Dictyostelium discoideum | 32 | ALA1148603 | organism-based format | Scientific Literature | |
6. | ALA998577 | Binding | Inhibition of the ATP-mediated HIV1 reverse transcriptase D67N/K70R/T215F/K219Q mutant catalyzed 3'-azido, 3'-deoxythymidine excision from AZT-terminated DNA primers | Human immunodeficiency virus 1 | 35 | ALA1141713 | assay format | Scientific Literature | |
7. | ALA998578 | Toxicity | Toxicity against human MCF7 cells assessed as growth inhibition by broth microdilution method | Homo sapiens | 25 | ALA1141713 | cell-based format | Scientific Literature | |
8. | ALA998579 | Toxicity | Toxicity against human SF268 cells assessed as growth inhibition by broth microdilution method | Homo sapiens | 25 | ALA1141713 | cell-based format | Scientific Literature | |
9. | ALA998580 | Toxicity | Toxicity against human NCI-H460 cells assessed as growth inhibition by broth microdilution method | Homo sapiens | 25 | ALA1141713 | cell-based format | Scientific Literature | |
10. | ALA998581 | Binding | Inhibition of the ATP-mediated HIV1 reverse transcriptase D67N/K70R/T215F/K219Q mutant catalyzed DNA synthesis | Human immunodeficiency virus 1 | 25 | ALA1141713 | assay format | Scientific Literature | |
11. | ALA927022 | Binding | Inhibition of Trypanosoma cruzi hexokinase | Trypanosoma cruzi | 12 | ALA1147071 | single protein format | Scientific Literature |