# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA880254 | Binding | Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coli | Trypanosoma brucei | 81 | ALA1141094 | assay format | Scientific Literature | |
2. | ALA865780 | Binding | Inhibitory activity against Trypanosoma cruzi hexokinase | Trypanosoma cruzi | 42 | ALA1148603 | single protein format | Scientific Literature | |
3. | ALA863956 | Functional | Cytotoxicity in human nasopharyngeal carcinoma KB cell line | Homo sapiens | 32 | ALA1148603 | cell-based format | Scientific Literature | |
4. | ALA865754 | ADME | Therapeutic index TI=LD50(KB)/IC50(TcHK) | 32 | ALA1148603 | assay format | Scientific Literature | ||
5. | ALA865755 | Functional | Cytotoxicity to Dictyostelium discoideum | Dictyostelium discoideum | 32 | ALA1148603 | organism-based format | Scientific Literature | |
6. | ALA927022 | Binding | Inhibition of Trypanosoma cruzi hexokinase | Trypanosoma cruzi | 12 | ALA1147071 | single protein format | Scientific Literature | |
7. | ALA3067708 | Binding | Inhibition of Arabidopsis thaliana P5C reductase catalytic activity assessed as inhibition of NADPH oxidation at 340 nm OD at 0.2 mM by NADPH oxidation assay | Arabidopsis thaliana | 26 | ALA3046072 | single protein format | Scientific Literature | |
8. | ALA3067709 | Binding | Inhibition of Arabidopsis thaliana P5C reductase catalytic activity assessed as residual concentration of enzyme at 535 nm OD at 0.5 mM by P5C utilization assay | Arabidopsis thaliana | 26 | ALA3046072 | single protein format | Scientific Literature | |
9. | ALA3079738 | Binding | Inhibition of Oryza sativa cv. Gigante vercellese (rice) glutamine synthetase assessed as inhibition of glutamine synthesis from glutamic acid at 1 mM after 15 min by biosynthetic assay | Oryza sativa | 18 | ALA3046691 | single protein format | Scientific Literature | |
10. | ALA3079739 | Binding | Inhibition of Oryza sativa cv. Gigante vercellese (rice) glutamine synthetase at 1 mM after 30 min by hemibiosynthetic assay | Oryza sativa | 18 | ALA3046691 | single protein format | Scientific Literature | |
11. | ALA3079740 | Binding | Inhibition of Oryza sativa cv. Gigante vercellese (rice) glutamine synthetase at 1 mM by transferase assay | Oryza sativa | 18 | ALA3046691 | single protein format | Scientific Literature | |
12. | ALA3075491 | Binding | Inhibition of Oryza sativa cv. Gigante vercellese (rice) glutamine synthetase assessed as inhibition of glutamine synthesis from glutamic acid after 15 min by biosynthetic assay | Oryza sativa | 11 | ALA3046691 | single protein format | Scientific Literature | |
13. | ALA3075492 | Binding | Inhibition of Oryza sativa cv. Gigante vercellese (rice) glutamine synthetase after 30 min by hemibiosynthetic assay | Oryza sativa | 11 | ALA3046691 | single protein format | Scientific Literature | |
14. | ALA3075493 | Binding | Inhibition of Oryza sativa cv. Gigante vercellese (rice) glutamine synthetase by transferase assay | Oryza sativa | 11 | ALA3046691 | single protein format | Scientific Literature | |
15. | ALA2444359 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 100 uM after 48 hrs by MTT assay | Homo sapiens | 23 | ALA2439950 | cell-based format | Scientific Literature | |
16. | ALA2444629 | Functional | Cytotoxicity against mouse J774A1 cells assessed as cell viability at 100 uM after 48 hrs by MTT assay | Mus musculus | 23 | ALA2439950 | cell-based format | Scientific Literature | |
17. | ALA2444630 | Binding | Binding affinity to bone mineral hydroxyapatite assessed as adsorbed level at 100 uM after 2 hrs by UV-spectrophotometric analysis | 23 | ALA2439950 | assay format | Scientific Literature | ||
18. | ALA2444631 | Binding | Inhibition of MMP14 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay | Homo sapiens | 24 | ALA2439950 | single protein format | Scientific Literature | |
19. | ALA2444632 | Binding | Inhibition of MMP9 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay | Homo sapiens | 24 | ALA2439950 | single protein format | Scientific Literature | |
20. | ALA2444633 | Binding | Inhibition of MMP8 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay | Homo sapiens | 24 | ALA2439950 | single protein format | Scientific Literature |