| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA883661 | B | Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degree C for 1 hr at pH 7.4 using [3H]Ntau(1)-Me-His-TRH; Range = 0.27-0.37 uM | 1 | ALA1141095 | cell-based format | Scientific Literature | ||
| 2. | ALA883662 | B | Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degree C for 1 hr at pH 7.4 using [3H]Ntau(1)-Me-His-TRH; Range = 0.12-0.24 uM | 1 | ALA1141095 | cell-based format | Scientific Literature | ||
| 3. | ALA872069 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8; Range = 0.16-0.51 uM | 1 | ALA1141095 | cell-based format | Scientific Literature | ||
| 4. | ALA872190 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8; Range = 0.011-0.052 uM | 1 | ALA1141095 | cell-based format | Scientific Literature | ||
| 5. | ALA883393 | B | Selectivity for thyrotropin releasing hormone receptor 2 measured as ratio of Ki towards THR-R1 to that of THR-R2 | 1 | ALA1141095 | assay format | Scientific Literature | ||
| 6. | ALA856223 | B | Selectivity for thyrotropin releasing hormone receptor 2 measured as ratio of signaling potency (EC50 for expressing CREB-luciferase reporter) towards THR-R1 to that of THR-R2 | 5 | ALA1141095 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!