| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA872292 | B | Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degree C for 1 hr at pH 7.4 using [3H]Ntau(1)-Me-His-TRH | 6 | ALA1141095 | cell-based format | Scientific Literature | ||
| 2. | ALA872293 | B | Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degree C for 1 hr at pH 7.4 using [3H]Ntau(1)-Me-His-TRH | 6 | ALA1141095 | cell-based format | Scientific Literature | ||
| 3. | ALA884981 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8 | 6 | ALA1141095 | cell-based format | Scientific Literature | ||
| 4. | ALA885039 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 h at 37 degree C and pH 7.8; Range = 0.69-3.2 uM | 1 | ALA1141095 | cell-based format | Scientific Literature | ||
| 5. | ALA856223 | B | Selectivity for thyrotropin releasing hormone receptor 2 measured as ratio of signaling potency (EC50 for expressing CREB-luciferase reporter) towards THR-R1 to that of THR-R2 | 5 | ALA1141095 | assay format | Scientific Literature |
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