# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA857972 | Binding | In vitro binding affinity towards (alpha-4)2(beta-2)3 neuronal nicotinic acetylcholine receptor in P2 membrane fractions of rat forebrain | 66 | ALA1144890 | cell membrane format | Scientific Literature | ||
2. | ALA635214 | ADME | Ionization constant was determined | 1 | ALA1123150 | assay format | Scientific Literature | ||
3. | ALA682820 | Functional | Agonist efficacy was evaluated as concentration that produces 10-m V depolarization in frog sartorius muscle; activity value ranges from 0.2-0.4 | frog | 1 | ALA1123150 | tissue-based format | Scientific Literature | |
4. | ALA822881 | Functional | Ability to stimulate catechloamine release in bovine adrenal chromaffin cells | Bos taurus | 1 | ALA1130264 | organism-based format | Scientific Literature | |
5. | ALA848250 | Binding | Ratio of Ki (binding affinity) relative to activation potency | 6 | ALA1135438 | assay format | Scientific Literature | ||
6. | ALA1794499 | Functional | PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] | 13,676 | ALA1201862 | assay format | PubChem BioAssays | ||
7. | ALA781256 | Functional | Effective dose required to produce prostration after injection into rat's fourth ventricle | Rattus norvegicus | 6 | ALA1124049 | organism-based format | Scientific Literature | |
8. | ALA794372 | Functional | Potency for prostration assay, relative to PHT | Rattus norvegicus | 6 | ALA1124049 | organism-based format | Scientific Literature | |
9. | ALA748710 | Functional | Compound was evaluated for functional potency and efficacy at rat Nicotinic acetylcholine receptor subtype DA release | Rattus norvegicus | 1 | ALA1130264 | assay format | Scientific Literature | |
10. | ALA748858 | Binding | Binding affinity towards nicotinic acetylcholine receptor using [125I]alpha-bungarotoxin as radioligand in rat forebrain homogenates | 34 | ALA1136338 | tissue-based format | Scientific Literature | ||
11. | ALA747854 | Binding | Binding affinity towards nicotinic acetylcholine receptor using [3H]-cytisine as radioligand in rat forebrain homogenates | 66 | ALA1136338 | tissue-based format | Scientific Literature | ||
12. | ALA747855 | Binding | Compound was evaluated for inhibitory activity towards nicotinic acetylcholine receptor in rat P2 brain membranes using [3H]nicotine as a radioligand | Rattus norvegicus | 3 | ALA1151545 | cell membrane format | Scientific Literature | |
13. | ALA747857 | Binding | Inhibition of (-)-[3H]nicotine binding to rat brain membranes | Rattus norvegicus | 6 | ALA1124049 | cell membrane format | Scientific Literature | |
14. | ALA872834 | Binding | Inhibition of [3H]MCC binding to rat brain membranes | Rattus norvegicus | 6 | ALA1124049 | cell membrane format | Scientific Literature | |
15. | ALA750360 | Binding | Compound was evaluated for potency towards nicotinic acetylcholine receptor in rat P2 brain membranes using [3H]nicotine as a radioligand | Rattus norvegicus | 3 | ALA1151545 | cell membrane format | Scientific Literature | |
16. | ALA750382 | Binding | Potency relative to PHT in rat brain membranes ([3H]MCC binding) | Rattus norvegicus | 6 | ALA1124049 | cell membrane format | Scientific Literature | |
17. | ALA750383 | Binding | Potency relative to PHT in rat brain membranes ([3H]nicotine binding) | Rattus norvegicus | 5 | ALA1124049 | cell membrane format | Scientific Literature | |
18. | ALA748731 | Binding | Inhibition of [3H]MCC binding to torpedo electroplax membranes | Torpedo | 6 | ALA1124049 | assay format | Scientific Literature | |
19. | ALA748732 | Binding | inhibition of (-)-[3H]nicotine binding to torpedo electroplax membranes | Torpedo | 6 | ALA1124049 | assay format | Scientific Literature | |
20. | ALA748733 | Binding | Potency relative to PHT in torpedo electroplax membranes ([3H]MCC binding) | Torpedo | 6 | ALA1124049 | cell membrane format | Scientific Literature |