# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA863349 | B | Inhibitory activity against papain using Z-Phe-Arg-NHNp substrate | Carica papaya | 48 | ALA1141197 | single protein format | Scientific Literature | |
2. | ALA863350 | B | Inhibitory activity against bovine cathepsin L using Z-Phe-Arg-NHMec substrate | Bos taurus | 48 | ALA1141197 | single protein format | Scientific Literature | |
3. | ALA864504 | B | Inhibitory activity against human cathepsin S using Z-Val-Val-Arg-NHMec substrate | Homo sapiens | 48 | ALA1141197 | single protein format | Scientific Literature | |
4. | ALA864505 | B | Inhibitory activity against human cathepsin K using Z-Leu-Arg-NHMec substrate | Homo sapiens | 48 | ALA1141197 | single protein format | Scientific Literature | |
5. | ALA3364438 | B | Inhibition of papaya papain using Z-Phe-Arg-pNA substrate by spectrophotometry | Carica papaya | 16 | ALA3351912 | single protein format | Scientific Literature | |
6. | ALA3807026 | B | Inhibition of human liver cathepsin B using Cbz-Arg-Arg-pNA as substrate at pH 6 incubated for 30 mins measured for 20 mins by photometrical analysis | Homo sapiens | 66 | ALA3804805 | assay format | Scientific Literature | |
7. | ALA4700264 | B | Covalent inhibition of Trypanosoma cruzi cruzipain using Z-Phe-Arg-7-amidomethylcoumarin as substrate measured after 5 mins by fluorometric analysis | Trypanosoma cruzi | 14 | ALA4699421 | single protein format | Scientific Literature | |
8. | ALA4700266 | F | Trypanocidal activity against Trypanosoma cruzi Tulahuen LacZ intracellular amastigote form infected in monkey LLC-MK2 cells incubated for 72 hrs by chlorophenol red beta-D-galactopyranoside substrate based spectrophotometric assay | Trypanosoma cruzi | 17 | ALA4699421 | organism-based format | Scientific Literature | |
9. | ALA4700268 | A | Cytotoxicity against monkey LLC-MK2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Macaca mulatta | 17 | ALA4699421 | cell-based format | Scientific Literature | |
10. | ALA4700272 | P | Glutathione reactivity in pH 7.4 phosphate buffer assessed as half life at 2.5 mM by HPLC analysis | 5 | ALA4699421 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4700273 | P | L-Cysteine reactivity in pH 7.4 phosphate buffer assessed as half life at 2.5 mM by HPLC analysis | 5 | ALA4699421 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA4700275 | P | L-Cysteine reactivity in pH 7.4 phosphate buffer assessed as decay constant | 4 | ALA4699421 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA4703665 | B | Inhibition of Leishmania mexicana CPB delta CTE mutant using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluorimetric assay | Leishmania mexicana | 36 | ALA4699568 | assay format | Scientific Literature | |
14. | ALA4703666 | A | Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluorimetric assay | Homo sapiens | 36 | ALA4699568 | single protein format | Scientific Literature | |
15. | ALA4703667 | B | Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluorimetric assay | Trypanosoma cruzi | 36 | ALA4699568 | single protein format | Scientific Literature | |
16. | ALA5244932 | B | Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constant | Trypanosoma cruzi | 14 | ALA5244221 | single protein format | Scientific Literature |