# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA868712 | B | Inhibitory activity against human 11beta-HSD1 | Homo sapiens | 24 | single protein format | Scientific Literature | ||
2. | ALA868713 | B | Inhibitory activity against mouse 11beta-HSD1 | Mus musculus | 24 | single protein format | Scientific Literature | ||
3. | ALA869362 | A | AUC in mouse | Mus musculus | 1 | organism-based format | Scientific Literature | ||
4. | ALA868717 | A | AUC in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
5. | ALA868718 | A | AUC in dog | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
6. | ALA868722 | A | Plasma clearance in mouse | Mus musculus | 3 | organism-based format | Scientific Literature | ||
7. | ALA867561 | A | Plasma clearance in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA867562 | A | plasma clearance in dog | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
9. | ALA867563 | A | Half life in mouse | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA867564 | A | Half life in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
11. | ALA867565 | A | Half life in dog | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
12. | ALA867566 | A | Oral bioavailability in mouse | Mus musculus | 3 | organism-based format | Scientific Literature | ||
13. | ALA867567 | A | Oral bioavailability in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
14. | ALA867568 | A | Oral bioavailability in dog | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
15. | ALA869368 | F | In vivo inhibition of 11beta-HSD1 at 4 hr (10 mg/kg, po) assessed by extent of cortisone to cortisol conversion | 13 | organism-based format | Scientific Literature | |||
16. | ALA869369 | F | In vivo inhibition of 11beta-HSD1 at 16 hr (10 mg/kg, po) assessed by extent of cortisone to cortisol conversion | 11 | organism-based format | Scientific Literature | |||
17. | ALA934096 | B | Inhibition of 11beta-HSD1 | 69 | single protein format | Scientific Literature | |||
18. | ALA977261 | B | Inhibition of human 11beta-HSD1 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
19. | ALA977262 | B | Inhibition of human 11beta-HSD2 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
20. | ALA1013588 | B | Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISA | Homo sapiens | 22 | cell-based format | Scientific Literature |