# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA630397 | A | Mouse plasma levels are obtained 24 hr after oral administration of 100 mg/kg of compound. | Mus musculus | 8 | ALA1132549 | organism-based format | Scientific Literature | |
2. | ALA630398 | A | Mouse plasma levels are obtained 6 hr after oral administration of 100 mg/kg of compound. | Mus musculus | 9 | ALA1132549 | organism-based format | Scientific Literature | |
3. | ALA635920 | P | LogD value determined at a pH of 7.4 | 4 | ALA1135889 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA635930 | P | Partition coefficient (logP) calculated from LogD | 4 | ALA1135889 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA645148 | P | pKa value at a pH of 7.4.value ranges from 7.2-4.2. | 1 | ALA1135889 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA634083 | A | Plasma levels following administration of 100 mg/Kg perorally and concentration in plasma 24 hr after administration | 4 | ALA1135889 | cell-free format | Scientific Literature | ||
7. | ALA634084 | A | Plasma levels following administration of 100 mg/Kg perorally and concentration in plasma 6 hr after administration | 4 | ALA1135889 | cell-free format | Scientific Literature | ||
8. | ALA639875 | P | solubility was determined using free base at pH 7 | 2 | ALA1135889 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA677388 | B | Inhibition of epidermal growth factor receptor kinase activity at a concentration of 2 uM of ATP | 30 | ALA1135889 | single protein format | Scientific Literature | ||
10. | ALA678320 | B | FGFR-1 (FTK) inhibitory activity at 2 uM of ATP in vitro. | 33 | ALA1132549 | single protein format | Scientific Literature | ||
11. | ALA676971 | B | Inhibition fibroblast growth factor receptor TK kinase activity at a concentration of 2 uM | 31 | ALA1135889 | single protein format | Scientific Literature | ||
12. | ALA678756 | B | Inhibition of fms-like tyrosine kinase receptor (Flt-1) kinase activity at a concentration of 2 uM of ATP | 31 | ALA1135889 | single protein format | Scientific Literature | ||
13. | ALA691872 | F | Inhibition of basal unstimulated growth of human endothelial cell | Homo sapiens | 30 | ALA1135889 | cell-based format | Scientific Literature | |
14. | ALA691873 | F | Inhibition of human endothelial cell growth stimulate by endothelial growth factor | Homo sapiens | 30 | ALA1135889 | cell-based format | Scientific Literature | |
15. | ALA691874 | F | Inhibition of human endothelial cell growth stimulate by vascular endothelial growth factor | Homo sapiens | 30 | ALA1135889 | cell-based format | Scientific Literature | |
16. | ALA800092 | F | Percent inhibition of VEGF-mediated estradiol benzoate-induced rat uterus weight gain at 100 mg/kg oral dose | Rattus norvegicus | 2 | ALA1132549 | organism-based format | Scientific Literature | |
17. | ALA811931 | B | In vitro vascular endothelial growth factor receptor 1 inhibitory activity at 2 uM of ATP. | 35 | ALA1132549 | single protein format | Scientific Literature | ||
18. | ALA812620 | B | Vascular endothelial growth factor receptor 2 inhibitory activity at 2 uM of ATP in vitro. | 33 | ALA1132549 | single protein format | Scientific Literature | ||
19. | ALA817494 | B | Inhibition of vascular endothelial growth factor receptor 2 kinase activity at a concentration of 2 uM | 31 | ALA1135889 | single protein format | Scientific Literature | ||
20. | ALA852072 | B | Ratio of IC50 of FGFR-1 (FTK) to VEGFR-1 (Flt). | 28 | ALA1132549 | assay format | Scientific Literature |