# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA863458 | B | Inhibitory activity against human thrombin at 2 uM | Homo sapiens | 34 | single protein format | Scientific Literature | ||
2. | ALA863459 | B | Inhibitory activity against human FXa at 5 uM | Homo sapiens | 34 | single protein format | Scientific Literature | ||
3. | ALA863460 | B | Selectivity ratio for human thrombin over human FXa | Homo sapiens | 3 | protein format | Scientific Literature | ||
4. | ALA863461 | B | Selectivity ratio for human thrombin over bovine trypsin | 3 | assay format | Scientific Literature | |||
5. | ALA4606117 | B | Inhibition of N-terminal SUMO and His6-tagged human KLK7 expressed in Escherichia coli Rosetta (DE3) pLysS assessed as reduction in covalent KLK7-vaspin complex formation using compound pre-treated KLK7 incubated for 60 mins by Coomassie-staining based SDS-PAGE method | Homo sapiens | 3 | assay format | Scientific Literature | ||
6. | ALA4606118 | B | Inhibition of N-terminal SUMO and His6-tagged human KLK7 assessed as reduction in vaspin-N-terminal cleavage using compound pre-treated KLK7 incubated for 60 mins by Coomassie-staining based SDS-PAGE method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
7. | ALA4606119 | B | Inhibition of N-terminal SUMO and His6-tagged human KLK7 assessed as protease activity by measuring fluorogenic peptide substrate NFF-3 cleavage (Rvb = >400 pmol/(min.ug) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
8. | ALA4606120 | B | Covalent binding affinity to of N-terminal SUMO and His6-tagged human KLK7 expressed in Escherichia coli Rosetta (DE3) pLysS assessed as compound binding to His57 of catalytic triad by mass spectrometry | Homo sapiens | 1 | assay format | Scientific Literature | ||
9. | ALA4606121 | P | Stability in 100% DMSO at -20 degC for several months by ESI-MS and 1H NMR spectroscopy | 1 | small-molecule physicochemical format | Scientific Literature |