# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA864074 | B | Inhibitory activity against humanized rabbit Cathepsin K | Homo sapiens | 40 | ALA1149395 | single protein format | Scientific Literature | |
2. | ALA864076 | B | Selectivity for Cathepsin L over Cathepsin K | 22 | ALA1149395 | protein format | Scientific Literature | ||
3. | ALA864077 | B | Selectivity for Cathepsin B over Cathepsin K | 22 | ALA1149395 | protein format | Scientific Literature | ||
4. | ALA864078 | B | Selectivity for Cathepsin S over Cathepsin K | 22 | ALA1149395 | protein format | Scientific Literature | ||
5. | ALA864079 | A | Half life in rat at 10 mL/kg, po | Rattus norvegicus | 9 | ALA1149395 | organism-based format | Scientific Literature | |
6. | ALA864080 | A | Plasma clearance in rat at 10 mL/kg, po | Rattus norvegicus | 9 | ALA1149395 | organism-based format | Scientific Literature | |
7. | ALA858799 | B | Inhibitory activity against rabbit Cathepsin K | Oryctolagus cuniculus | 10 | ALA1149395 | single protein format | Scientific Literature | |
8. | ALA867017 | A | Oral bioavailability in rats at 10 mL/kg, po | Rattus norvegicus | 9 | ALA1149395 | organism-based format | Scientific Literature | |
9. | ALA886076 | B | Inhibition of humaized rabbit cathepsin K | Homo sapiens | 10 | ALA1139919 | single protein format | Scientific Literature | |
10. | ALA886077 | B | Inhibition of rabbit cathepsin K | Oryctolagus cuniculus | 10 | ALA1139919 | single protein format | Scientific Literature | |
11. | ALA886078 | B | Selectivity for human cathepsin K over human cathepsin L | Homo sapiens | 10 | ALA1139919 | assay format | Scientific Literature | |
12. | ALA886079 | B | Selectivity for human cathepsin K over human cathepsin B | Homo sapiens | 10 | ALA1139919 | assay format | Scientific Literature | |
13. | ALA886080 | B | Selectivity for human cathepsin K over human cathepsin S | Homo sapiens | 10 | ALA1139919 | assay format | Scientific Literature | |
14. | ALA886081 | F | Inhibition of bone resorption in New Zealand white hare by crosslaps ELISA assay | Oryctolagus cuniculus | 10 | ALA1139919 | organism-based format | Scientific Literature | |
15. | ALA886082 | F | Selectivity for IC50 of new Zealand white hare bone resorption over IC50 rabbit cathepsin K | Oryctolagus cuniculus | 10 | ALA1139919 | assay format | Scientific Literature | |
16. | ALA886086 | A | Oral bioavailability in rat at 10 mg/kg | Rattus norvegicus | 2 | ALA1139919 | organism-based format | Scientific Literature | |
17. | ALA886087 | A | Half life in rat at 10 mg/kg, po or 5 mg/kg, iv | Rattus norvegicus | 2 | ALA1139919 | organism-based format | Scientific Literature | |
18. | ALA886088 | A | AUC in rat at 10 mg/kg, po or 5 mg/kg, iv | Rattus norvegicus | 2 | ALA1139919 | organism-based format | Scientific Literature |