# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA864074 | Binding | Inhibitory activity against humanized rabbit Cathepsin K | Homo sapiens | 40 | ALA1149395 | single protein format | Scientific Literature | |
2. | ALA864076 | Binding | Selectivity for Cathepsin L over Cathepsin K | 22 | ALA1149395 | protein format | Scientific Literature | ||
3. | ALA864077 | Binding | Selectivity for Cathepsin B over Cathepsin K | 22 | ALA1149395 | protein format | Scientific Literature | ||
4. | ALA864078 | Binding | Selectivity for Cathepsin S over Cathepsin K | 22 | ALA1149395 | protein format | Scientific Literature | ||
5. | ALA864079 | ADME | Half life in rat at 10 mL/kg, po | Rattus norvegicus | 9 | ALA1149395 | organism-based format | Scientific Literature | |
6. | ALA864080 | ADME | Plasma clearance in rat at 10 mL/kg, po | Rattus norvegicus | 9 | ALA1149395 | organism-based format | Scientific Literature | |
7. | ALA859620 | ADME | Half life in dog at 5 mL/kg, po | Canis lupus familiaris | 5 | ALA1149395 | organism-based format | Scientific Literature | |
8. | ALA859583 | ADME | Plasma clearance in dog at 5 mL/kg, po | Canis lupus familiaris | 5 | ALA1149395 | organism-based format | Scientific Literature | |
9. | ALA859584 | ADME | Half life in squirrel monkey at 1 mL/kg, po | Saimiri sciureus | 6 | ALA1149395 | organism-based format | Scientific Literature | |
10. | ALA859586 | ADME | Plasma clearance in squirrel monkey at 1 mL/kg, po | Saimiri sciureus | 6 | ALA1149395 | organism-based format | Scientific Literature | |
11. | ALA859585 | Functional | Effect on degradation of collagen in bovine bone by rabbit osteoclast | Oryctolagus cuniculus | 5 | ALA1149395 | organism-based format | Scientific Literature | |
12. | ALA858799 | Binding | Inhibitory activity against rabbit Cathepsin K | Oryctolagus cuniculus | 10 | ALA1149395 | single protein format | Scientific Literature | |
13. | ALA869999 | ADME | Oral bioavailability in dogs at 5 mL/kg, po | Canis lupus familiaris | 5 | ALA1149395 | organism-based format | Scientific Literature | |
14. | ALA867017 | ADME | Oral bioavailability in rats at 10 mL/kg, po | Rattus norvegicus | 9 | ALA1149395 | organism-based format | Scientific Literature | |
15. | ALA865161 | ADME | Oral bioavailability in squirrel monkey at 1 mL/kg, po | Saimiri sciureus | 6 | ALA1149395 | organism-based format | Scientific Literature | |
16. | ALA1023819 | ADME | Protein binding in rat plasma by ultracentrifugation | Rattus norvegicus | 1 | ALA1140150 | cell-free format | Scientific Literature | |
17. | ALA1023820 | ADME | Protein binding in rabbit plasma by ultracentrifugation | Oryctolagus cuniculus | 1 | ALA1140150 | cell-free format | Scientific Literature | |
18. | ALA1023821 | ADME | Protein binding in human plasma by ultracentrifugation | Homo sapiens | 1 | ALA1140150 | cell-free format | Scientific Literature | |
19. | ALA1023822 | Binding | Inhibition of humanized rabbit cathepsin K Tyr61Asp and Val157Leu mutant | Homo sapiens | 6 | ALA1140150 | assay format | Scientific Literature | |
20. | ALA1023823 | Binding | Inhibition of rabbit cathepsin K | Oryctolagus cuniculus | 6 | ALA1140150 | single protein format | Scientific Literature |
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