# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615302 | Binding | Binding affinity for 3-beta-hydroxysteroid dehydrogenase | Homo sapiens | 13 | ALA1129998 | single protein format | Scientific Literature | |
2. | ALA615557 | Binding | In vitro inhibitory activity against human adrenal 3-beta hydroxy-delta 5-teroid isomerase | 71 | ALA1127590 | assay format | Scientific Literature | ||
3. | ALA625390 | ADME | Bioavailability in dog (male Beagle) i.v. administration | Canis lupus familiaris | 1 | ALA1127590 | organism-based format | Scientific Literature | |
4. | ALA635655 | ADME | Bioavailability after oral administration in dog | Canis lupus familiaris | 1 | ALA1126579 | organism-based format | Scientific Literature | |
5. | ALA636604 | ADME | Half-life after intravenous administration of 5 mg/kg/day dose in male beagles | Canis lupus familiaris | 4 | ALA1127590 | organism-based format | Scientific Literature | |
6. | ALA635807 | ADME | Half-life in dog | Canis lupus familiaris | 3 | ALA1126579 | organism-based format | Scientific Literature | |
7. | ALA701910 | Binding | Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutes | 22 | ALA1126579 | single protein format | Scientific Literature | ||
8. | ALA873205 | Binding | Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutes | 23 | ALA1126579 | single protein format | Scientific Literature | ||
9. | ALA809999 | Binding | Binding affinity for human 5-alpha reductase 2 isozyme | Homo sapiens | 13 | ALA1129998 | single protein format | Scientific Literature | |
10. | ALA810001 | Binding | In vitro inhibitory activity against human type 2 5-alpha reductase | 71 | ALA1127590 | single protein format | Scientific Literature | ||
11. | ALA816493 | Binding | Binding affinity for human 5 alpha reductase 1 isozyme | Homo sapiens | 13 | ALA1129998 | single protein format | Scientific Literature | |
12. | ALA816494 | Binding | In vitro inhibitory activity against human type 1 5-alpha reductase | 70 | ALA1127590 | single protein format | Scientific Literature | ||
13. | ALA790603 | Functional | In vivo evaluation in chronic castrated rat to inhibit T-stimulated prostate growth expressed as percentage reduction | Rattus norvegicus | 10 | ALA1126579 | organism-based format | Scientific Literature | |
14. | ALA790605 | Functional | In vivo inhibition of T stimulated prostate growth in rats was reported after oral administration at a dose 5 mg/kg/day | Rattus norvegicus | 4 | ALA1127590 | organism-based format | Scientific Literature |