# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA859247 | B | Inhibitory activity against human PARP1 expressed in PC12 cells | Homo sapiens | 17 | ALA1148616 | cell-based format | Scientific Literature | |
2. | ALA860595 | B | Inhibition of recombinant human PARP1 | Homo sapiens | 22 | ALA1138164 | single protein format | Scientific Literature | |
3. | ALA901413 | B | Inhibition of human recombinant PARP1 in U251MG cells by CometAssay | Homo sapiens | 31 | ALA1138399 | cell-based format | Scientific Literature | |
4. | ALA901414 | F | Recovery of NAD+ in hydrogen peroxide treated PC12 cells at 1 uM relative to control | Rattus norvegicus | 31 | ALA1138399 | cell-based format | Scientific Literature | |
5. | ALA901415 | F | Maximum recovery of NAD+ in hydrogen peroxide treated PC12 cells at 30 uM relative to control | Rattus norvegicus | 27 | ALA1138399 | cell-based format | Scientific Literature | |
6. | ALA985370 | B | Inhibition of PARP1 in human BxPC3 cells assessed as increase in sensitization of cisplatin-induced cytotoxicity | Homo sapiens | 3 | ALA1151700 | cell-based format | Scientific Literature | |
7. | ALA985371 | B | Inhibition of PARP1 in human U2OS cells assessed as increase in sensitization of cisplatin-induced cytotoxicity | Homo sapiens | 3 | ALA1151700 | cell-based format | Scientific Literature | |
8. | ALA988048 | B | Inhibition of PARP1 in human NTera2 cells assessed as increase in sensitization of cisplatin-induced cytotoxicity | Homo sapiens | 3 | ALA1151700 | cell-based format | Scientific Literature | |
9. | ALA988049 | B | Inhibition of PARP1 in human HeLa cells assessed as increase in sensitization of cisplatin-induced cytotoxicity | Homo sapiens | 3 | ALA1151700 | cell-based format | Scientific Literature | |
10. | ALA1938153 | B | Inhibition of recombinant human PARP1 by in vitro assay | Homo sapiens | 27 | ALA1933047 | single protein format | Scientific Literature | |
11. | ALA1938154 | B | Inhibition of PARP1 in rat PC12 cells assessed as NAD+ recovery at 1 uM pre-treated for 1 hr before hydrogen peroxide addition followed by washout and compound treated again for 1 hr relative to control | Rattus norvegicus | 27 | ALA1933047 | cell-based format | Scientific Literature | |
12. | ALA1938156 | B | Inhibition of PARP1 in rat PC12 cells assessed as NAD+ recovery at 30 uM pre-treated for 1 hr before hydrogen peroxide addition followed by washout and compound treated again for 1 hr relative to 5H-phenanthridin-6-one | Rattus norvegicus | 18 | ALA1933047 | cell-based format | Scientific Literature |