# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA862304 | B | Inhibition of serotonin re-uptake at human serotonin transporter expressed in HEK293 cells | Homo sapiens | 40 | ALA1139648 | cell-based format | Scientific Literature | |
2. | ALA862305 | B | Inhibition of dopamine re-uptake at human dopamine transporter expressed in HEK293 cells | Homo sapiens | 40 | ALA1139648 | cell-based format | Scientific Literature | |
3. | ALA862356 | B | Inhibition of noradrenaline re-uptake at human noradrenaline transporter expressed in HEK293 cells | Homo sapiens | 40 | ALA1139648 | cell-based format | Scientific Literature | |
4. | ALA860403 | B | Selectivity for inhibition of serotonin re-uptake at human serotonin transporter over inhibition of dopamine re-uptake at human dopamine transporter | Homo sapiens | 5 | ALA1139648 | protein format | Scientific Literature | |
5. | ALA862357 | B | Selectivity for inhibition of serotonin re-uptake at human serotonin transporter over inhibition of noradrenaline re-uptake at human noradrenaline transporter | Homo sapiens | 5 | ALA1139648 | protein format | Scientific Literature | |
6. | ALA861178 | P | Distribution coefficient of the compound, log D | 5 | ALA1139648 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA861179 | P | Dissociation constant, pKa of the compound | 5 | ALA1139648 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA861180 | A | Permeability from apical to basolateral in Caco-2 cell membrane | Homo sapiens | 5 | ALA1139648 | cell-based format | Scientific Literature | |
9. | ALA861181 | A | Permeability from basolateral to apical in Caco-2 cell membrane | Homo sapiens | 5 | ALA1139648 | cell-based format | Scientific Literature | |
10. | ALA861182 | A | Ratio of permeability from apical to basolateral over basolateral to apical in Caco-2 cell membrane | Homo sapiens | 5 | ALA1139648 | cell-based format | Scientific Literature |