The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA862304 B Inhibition of serotonin re-uptake at human serotonin transporter expressed in HEK293 cells Homo sapiens 40 cell-based format Scientific Literature 2. ALA862305 B Inhibition of dopamine re-uptake at human dopamine transporter expressed in HEK293 cells Homo sapiens 40 cell-based format Scientific Literature 3. ALA862356 B Inhibition of noradrenaline re-uptake at human noradrenaline transporter expressed in HEK293 cells Homo sapiens 40 cell-based format Scientific Literature 4. ALA860403 B Selectivity for inhibition of serotonin re-uptake at human serotonin transporter over inhibition of dopamine re-uptake at human dopamine transporter Homo sapiens 5 protein format Scientific Literature 5. ALA862357 B Selectivity for inhibition of serotonin re-uptake at human serotonin transporter over inhibition of noradrenaline re-uptake at human noradrenaline transporter Homo sapiens 5 protein format Scientific Literature 6. ALA861178 P Distribution coefficient of the compound, log D 5 small-molecule physicochemical format Scientific Literature 7. ALA861179 P Dissociation constant, pKa of the compound 5 small-molecule physicochemical format Scientific Literature 8. ALA861180 A Permeability from apical to basolateral in Caco-2 cell membrane Homo sapiens 5 cell-based format Scientific Literature 9. ALA861181 A Permeability from basolateral to apical in Caco-2 cell membrane Homo sapiens 5 cell-based format Scientific Literature 10. ALA861182 A Ratio of permeability from apical to basolateral over basolateral to apical in Caco-2 cell membrane Homo sapiens 5 cell-based format Scientific Literature 11. ALA861183 A Half life in human liver microsome Homo sapiens 2 microsome format Scientific Literature 12. ALA861184 A Half life in rat liver microsome Rattus norvegicus 2 microsome format Scientific Literature 13. ALA861187 A Blood clearance in rat in CNS penetration assay at 3 mg/kg, iv or 5 mg/kg, po Rattus norvegicus 1 organism-based format Scientific Literature 14. ALA861188 A Volume of distribution in rat at 3 mg/kg, iv or 5 mg/kg, po Rattus norvegicus 1 organism-based format Scientific Literature 15. ALA861231 A Unbound volume of distribution in rat at 3 mg/kg, iv or 5 mg/kg, po Rattus norvegicus 1 organism-based format Scientific Literature 16. ALA861233 A Half life in rat at 3 mg/kg, iv or 5 mg/kg, po Rattus norvegicus 1 organism-based format Scientific Literature 17. ALA861235 A Oral bioavailability in rat at 5 mg/kg, po Rattus norvegicus 1 organism-based format Scientific Literature 18. ALA861237 A Tmax in rat at 3 mg/kg, iv or 5 mg/kg, po Rattus norvegicus 1 organism-based format Scientific Literature 19. ALA1012266 A Oral bioavailability in dog at 1 mg/kg Canis lupus familiaris 2 organism-based format Scientific Literature 20. ALA1012267 B Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells Homo sapiens 48 cell-based format Scientific Literature