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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA860941 B Inhibitory activity against VEGFR2 Homo sapiens 16 ALA1146078 single protein format Scientific Literature 2. ALA859787 A AUC in mice at 50 mg/kg after 4 hrs Mus musculus 10 ALA1146078 organism-based format Scientific Literature 3. ALA859788 A Cmax in mice at 50 mg/kg after 4 hrs Mus musculus 10 ALA1146078 organism-based format Scientific Literature 4. ALA859789 A Inhibitory activity against CYP3A4 Homo sapiens 10 ALA1146078 single protein format Scientific Literature 5. ALA859790 F Inhibitory activity against hERG by patch-clamp assay Homo sapiens 7 ALA1146078 assay format Scientific Literature 6. ALA3541057 A AUC (0 to t) in healthy human plasma treated with brivanib alaninate at 400 mg, po administered as single dose via gavage by LC/MS analysis Homo sapiens 1 ALA3525936 organism-based format Scientific Literature 7. ALA3541058 A Drug metabolism in rat liver cytosol assessed as sulfate metabolite formation by Michaelis-Menten equation in presence of NADPH Rattus norvegicus 2 ALA3525936 assay format Scientific Literature 8. ALA3541059 A Drug metabolism in monkey liver cytosol assessed as sulfate metabolite formation by Michaelis-Menten equation in presence of NADPH Macaca mulatta 2 ALA3525936 assay format Scientific Literature 9. ALA3536554 A Drug metabolism in human liver cytosol assessed as sulfate metabolite formation by Michaelis-Menten equation in presence of NADPH Homo sapiens 2 ALA3525936 assay format Scientific Literature 10. ALA3536555 B Inhibition of recombinant VEGFR-2 (unknown origin) Homo sapiens 2 ALA3525936 single protein format Scientific Literature 11. ALA3536556 B Inhibition of recombinant FGFR-1 (unknown origin) Homo sapiens 2 ALA3525936 single protein format Scientific Literature 12. ALA3536557 F Inhibition of VEGF-stimulated HUVEC cell proliferation assessed as 5-bromo-2-deoxyuridine incorporation Homo sapiens 2 ALA3525936 cell-based format Scientific Literature 13. ALA3536558 F Inhibition of FGF-stimulated HUVEC cell proliferation assessed as 5-bromo-2-deoxyuridine incorporation Homo sapiens 2 ALA3525936 cell-based format Scientific Literature 14. ALA3536559 F Inhibition of VEGF/FGF-stimulated HUVEC cell proliferation assessed as 5-bromo-2-deoxyuridine incorporation Homo sapiens 2 ALA3525936 cell-based format Scientific Literature 15. ALA3531903 A Drug metabolism in monkey liver microsomes assessed as (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yloxy)propan-2-ol formation at 10 uM after 60 mins by LC/MS analysis in absence of NADPH Macaca mulatta 1 ALA3525936 assay format Scientific Literature 16. ALA3531904 A Drug metabolism in human liver microsomes assessed as (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yloxy)propan-2-ol formation at 10 uM after 60 mins by LC/MS analysis in absence of NADPH Homo sapiens 1 ALA3525936 assay format Scientific Literature 17. ALA3532252 A Cmax in Sprague-Dawley rat plasma treated with brivanib alaninate at 60 mg/kg, po administered as single dose via gavage by LC/MS analysis Rattus norvegicus 1 ALA3525936 organism-based format Scientific Literature 18. ALA3532253 A Tmax in Sprague-Dawley rat plasma treated with brivanib alaninate at 60 mg/kg, po administered as single dose via gavage by LC/MS analysis Rattus norvegicus 1 ALA3525936 organism-based format Scientific Literature 19. ALA3532254 A AUC (0 to t) in Sprague-Dawley rat plasma treated with brivanib alaninate at 60 mg/kg, po administered as single dose via gavage by LC/MS analysis Rattus norvegicus 1 ALA3525936 organism-based format Scientific Literature 20. ALA3532258 A Cmax in cynomolgus monkey plasma treated with brivanib alaninate at 10 mg/kg, po administered as single dose via gavage by LC/MS analysis Macaca fascicularis 1 ALA3525936 organism-based format Scientific Literature