# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA869602 | Binding | Inhibition of Plasmodium falciparum TrxR | Plasmodium falciparum | 10 | ALA1146972 | single protein format | Scientific Literature | |
2. | ALA869603 | Binding | Inhibition of human TrxR | Homo sapiens | 11 | ALA1146972 | protein format | Scientific Literature | |
3. | ALA861196 | Binding | Selectivity for Plasmodium falciparum TrxR over human TrxR | 10 | ALA1146972 | assay format | Scientific Literature | ||
4. | ALA869604 | Binding | Inhibition of human GR at 2 uM | Homo sapiens | 2 | ALA1146972 | single protein format | Scientific Literature | |
5. | ALA869606 | Binding | Inhibition of Plasmodium falciparum GR at 2 uM | Plasmodium falciparum | 2 | ALA1146972 | single protein format | Scientific Literature | |
6. | ALA869608 | Binding | Binding affinity to Plasmodium falciparum TrxR in presence of thioredoxin | Plasmodium falciparum | 3 | ALA1146972 | single protein format | Scientific Literature | |
7. | ALA869609 | Binding | Binding affinity to Plasmodium falciparum TrxR in presence of NADPH | Plasmodium falciparum | 3 | ALA1146972 | single protein format | Scientific Literature | |
8. | ALA869610 | Binding | Irreversible inhibition of Plasmodium falciparum TrxR at 100 uM relative to control | Plasmodium falciparum | 1 | ALA1146972 | single protein format | Scientific Literature | |
9. | ALA869611 | Binding | Irreversible inhibition of Plasmodium falciparum TrxR at 2 uM | Plasmodium falciparum | 1 | ALA1146972 | single protein format | Scientific Literature | |
10. | ALA869612 | Binding | Reversible uncompetitive inhibition of Plasmodium falciparum TrxR at 2 uM | Plasmodium falciparum | 1 | ALA1146972 | single protein format | Scientific Literature | |
11. | ALA869613 | Functional | Growth inhibition against Plasmodium falciparum K1 | Plasmodium falciparum | 4 | ALA1146972 | organism-based format | Scientific Literature |