# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA869603 | Binding | Inhibition of human TrxR | Homo sapiens | 11 | ALA1146972 | protein format | Scientific Literature | |
2. | ALA863811 | Binding | Inhibition of Plasmodium falciparum TrxR at 100 uM | Plasmodium falciparum | 1 | ALA1146972 | single protein format | Scientific Literature | |
3. | ALA3789850 | Functional | Protective activity against Daboia russellii venom-induced mortality by measuring venom LD50 in Swiss albino mouse at 100 mmol, iv preincubated with venom for 1 hr followed by administration to mouse measured after 24 hrs (Rvb = 2.28 ug) | Daboia russelii | 37 | ALA3785074 | organism-based format | Scientific Literature | |
4. | ALA3789852 | Functional | Protective activity against Naja kaouthia venom-induced mortality in Swiss albino mouse at 100 mmol, iv by measuring venom LD50 preincubated with venom for 1 hr followed by administration to mouse measured after 24 hrs (Rvb = 2.82 ug) | Naja kaouthia | 37 | ALA3785074 | organism-based format | Scientific Literature | |
5. | ALA3789854 | Functional | Protective activity against Daboia russellii venom-induced hemorrhage in intradermally dosed Swiss albino mouse at 100 mmol assessed as hemorhagic lesion by measuring minimal hemolytic dose preincubated with venom for 1 hr followed by administration to mouse measured after 24 hrs (Rvb = 5 ug) | Daboia russelii | 37 | ALA3785074 | organism-based format | Scientific Literature | |
6. | ALA3789856 | Physicochemical | Lipophilicity, log P of compound | 36 | ALA3785074 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA3789857 | Functional | Protective activity against Daboia russellii venom-induced mortality in Swiss albino mouse at 100 mmol, iv by measuring venom LD50 administered immediately after venom injection measured after 24 hrs (Rvb = 2.28ug) | Daboia russelii | 37 | ALA3785074 | organism-based format | Scientific Literature | |
8. | ALA3789859 | Functional | Protective activity against Naja kaouthia venom-induced mortality in Swiss albino mouse at 100 mmol, iv by measuring venom LD50 administered immediately after venom injection measured after 24 hrs (Rvb = 2.82 ug) | Naja kaouthia | 37 | ALA3785074 | organism-based format | Scientific Literature | |
9. | ALA3789861 | Functional | Protective activity against Daboia russellii venom-induced hemorrhage in Swiss albino mouse at 100 mmol, iv assessed as hemorhagic lesion by measuring minimal hemolytic dose administered immediately after venom injection measured after 24 hrs (Rvb =5 ug) | Daboia russelii | 37 | ALA3785074 | organism-based format | Scientific Literature |