# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA870856 | F | Increase in ALP activity in mouse primary osteoblasts at 1 uM relative to control | Mus musculus | 7 | ALA1147800 | cell-based format | Scientific Literature | |
2. | ALA870857 | F | Increase in ALP activity in mouse primary osteoblasts at 10 uM relative to control | Mus musculus | 7 | ALA1147800 | cell-based format | Scientific Literature | |
3. | ALA870858 | F | Increase in ALP activity in mouse primary osteoblasts at 20 uM relative to control | Mus musculus | 7 | ALA1147800 | cell-based format | Scientific Literature | |
4. | ALA868172 | F | Effect on mineralization in mouse primary osteoblasts by measuring calcium deposition | Mus musculus | 3 | ALA1147800 | cell-based format | Scientific Literature | |
5. | ALA913665 | B | Inhibition of human Cathepsin K | Homo sapiens | 8 | ALA1146175 | single protein format | Scientific Literature | |
6. | ALA996509 | B | Inhibition of PDE in Sprague-Dawley rat epididymal adipose tissue assessed as [14C]adenosine recovery by liquid scintillation counting | Rattus norvegicus | 3 | ALA1151310 | tissue-based format | Scientific Literature | |
7. | ALA1211753 | B | Inhibition of BACE1 after 60 mins by FRET assay | 21 | ALA1208740 | single protein format | Scientific Literature | ||
8. | ALA1286520 | B | Non-competitive inhibition of SARS coronavirus 3C-like protease by Dixon plot analysis | SARS coronavirus | 4 | ALA1275337 | assay format | Scientific Literature | |
9. | ALA1286522 | B | Inhibition of SARS coronavirus 3C-like protease after 60 mins by FRET assay | SARS coronavirus | 16 | ALA1275337 | assay format | Scientific Literature | |
10. | ALA2175275 | F | Antimicrobial activity against axenically grown Leishmania donovani amastigotes | Leishmania donovani | 5 | ALA2169835 | organism-based format | Scientific Literature | |
11. | ALA3592586 | F | Neuroprotective activity against 0.1 uM amyloid beta 42-induced toxicity in rat PC12 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | Rattus norvegicus | 24 | ALA3588767 | cell-based format | Scientific Literature | |
12. | ALA4195640 | B | Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluorescence assay | Homo sapiens | 13 | ALA4190401 | single protein format | Scientific Literature | |
13. | ALA4195642 | F | Cytotoxicity against human MGC803 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4190401 | cell-based format | Scientific Literature | |
14. | ALA4195643 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4190401 | cell-based format | Scientific Literature | |
15. | ALA4195644 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4190401 | cell-based format | Scientific Literature | |
16. | ALA4195645 | F | Cytotoxicity against human T24 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4190401 | cell-based format | Scientific Literature | |
17. | ALA4195646 | B | Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluorescence assay | Homo sapiens | 13 | ALA4190401 | single protein format | Scientific Literature | |
18. | ALA4195647 | B | Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluorescence assay | Homo sapiens | 13 | ALA4190401 | single protein format | Scientific Literature | |
19. | ALA4390040 | B | Inhibition of human amyloid beta (1 to 40) assessed as reduction in aggregation measured after 24 hrs by ThT fluorescence assay | Homo sapiens | 29 | ALA4387742 | single protein format | Scientific Literature | |
20. | ALA5133308 | F | Cytotoxicity against human MCF7 cells measured after 24 hrs by MTT assay | Homo sapiens | 10 | ALA5131413 | cell-based format | Scientific Literature |