# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA869761 | B | Inhibition of Plasmodium falciparum dUTPase | Plasmodium falciparum | 41 | single protein format | Scientific Literature | ||
2. | ALA869762 | B | Inhibition of human recombinant dUTPase | Homo sapiens | 41 | single protein format | Scientific Literature | ||
3. | ALA870927 | F | Antiplasmodial activity against Plasmodium falciparum | Plasmodium falciparum | 42 | organism-based format | Scientific Literature | ||
4. | ALA870928 | F | Cytotoxicity against rat L6 cells | Rattus norvegicus | 42 | cell-based format | Scientific Literature | ||
5. | ALA870929 | B | Selectivity index, human dUTPase/Plasmodium falciparum dUTPase | Plasmodium falciparum | 26 | single protein format | Scientific Literature | ||
6. | ALA853392 | F | Selectivity index, IC50 for Plasmodium falciparum / IC50 for rat L6 cells | 26 | cell-based format | Scientific Literature | |||
7. | ALA1810452 | F | Antimalarial activity against blood stage Plasmodium falciparum infected in human red blood cells after 1 hr by propidium iodide staining based microscopic analysis | Plasmodium falciparum | 9 | organism-based format | Scientific Literature | ||
8. | ALA1810453 | B | Inhibition of recombinant wild type Plasmodium falciparum dUTPase expressed in Escherichia coli BL21(DE3) cells using dUTP as substrate by spectrophotometric analysis | Plasmodium falciparum | 9 | cell-based format | Scientific Literature | ||
9. | ALA1810454 | B | Inhibition of recombinant Plasmodium falciparum dUTPase F46A mutant expressed in Escherichia coli BL21(DE3) cells using dUTP as substrate by spectrophotometric analysis | Plasmodium falciparum | 9 | cell-based format | Scientific Literature | ||
10. | ALA1810455 | B | Inhibition of recombinant Plasmodium falciparum dUTPase K96A mutant expressed in Escherichia coli BL21(DE3) cells using dUTP as substrate by spectrophotometric analysis | Plasmodium falciparum | 9 | cell-based format | Scientific Literature | ||
11. | ALA1810456 | B | Inhibition of recombinant Plasmodium falciparum dUTPase I117A mutant expressed in Escherichia coli BL21(DE3) cells using dUTP as substrate by spectrophotometric analysis | Plasmodium falciparum | 9 | cell-based format | Scientific Literature | ||
12. | ALA1810457 | B | Inhibition of human dUTPase using dUTP as substrate by spectrophotometric analysis | Homo sapiens | 9 | single protein format | Scientific Literature | ||
13. | ALA1810458 | B | Selectivity index, ratio Ki for recombinant wild type Plasmodium falciparum dUTPase expressed in Escherichia coli BL21(DE3) cells to Ki for human dUTPase | 9 | cell-based format | Scientific Literature | |||
14. | ALA1810459 | B | Selectivity index, ratio of Ki for recombinant Plasmodium falciparum dUTPase F46A mutant expressed in Escherichia coli BL21(DE3) cells to Ki for human dUTPase | 9 | cell-based format | Scientific Literature | |||
15. | ALA1810460 | B | Selectivity index, ratio of Ki for recombinant Plasmodium falciparum dUTPase K96A mutant expressed in Escherichia coli BL21(DE3) cells to Ki for human dUTPase | 9 | cell-based format | Scientific Literature | |||
16. | ALA1810461 | B | Selectivity index, ratio of Ki for recombinant Plasmodium falciparum dUTPase I117A mutant expressed in Escherichia coli BL21(DE3) cells to Ki for human dUTPase | 9 | cell-based format | Scientific Literature | |||
17. | ALA957492 | B | Inhibition of Plasmodium falciparum dUTPase | Plasmodium falciparum | 14 | single protein format | Scientific Literature | ||
18. | ALA957493 | B | Inhibition of human dUTPase | Homo sapiens | 14 | single protein format | Scientific Literature | ||
19. | ALA957494 | B | Selectivity ratio of human dUTPase to Plasmodium falciparum dUTPase | 11 | assay format | Scientific Literature | |||
20. | ALA957495 | F | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1 infected erythrocytes | Plasmodium falciparum | 14 | organism-based format | Scientific Literature |