# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA866004 | B | Agonist like activity at skeletal junction sarcoplasmic reticulum RyR1/FKBP12 complex assessed as increase in [3H]ryanodine binding | Homo sapiens | 13 | protein complex format | Scientific Literature | ||
2. | ALA960265 | B | Displacement of [3H]ryanodine from RyR1 calcium channel in sarcoplasmic reticulum assessed as calcium mobilization | 5 | single protein format | Scientific Literature | |||
3. | ALA1006192 | B | Binding affinity to RYR1 channels by calcium mobilization assay | 5 | single protein format | Scientific Literature | |||
4. | ALA1006193 | B | Activity at RYR2 receptor in rat cerebellar granule neurons assessed as increase in intracellular calcium level at 20 uM | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
5. | ALA1006194 | B | Activity at RYR2 receptor in rat cerebellar granule neurons assessed activation of [45Ca2+] uptake at 20 uM after 10 mins | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
6. | ALA984030 | F | Antimicrobial activity against Neisseria gonorrhoeae ATCC 49226 after 16 hrs by disk susceptibility test | Neisseria gonorrhoeae | 10 | organism-based format | Scientific Literature | ||
7. | ALA984031 | F | Antimicrobial activity against Enterococcus faecalis ATCC 29212 after 16 hrs by disk susceptibility test | Enterococcus faecalis | 8 | organism-based format | Scientific Literature | ||
8. | ALA984032 | F | Antimicrobial activity against Staphylococcus aureus ATCC 29213 after 16 hrs by disk susceptibility test | Staphylococcus aureus | 9 | organism-based format | Scientific Literature | ||
9. | ALA984033 | F | Antimicrobial activity against Candida albicans ATCC 90028 up to 100 ug/disk after 42 hrs by disk susceptibility test | Candida albicans | 11 | organism-based format | Scientific Literature | ||
10. | ALA984034 | F | Antimicrobial activity against Cryptococcus neoformans ATCC 90112 up to 100 ug/disk after 42 hrs by disk susceptibility test | Cryptococcus neoformans | 11 | organism-based format | Scientific Literature | ||
11. | ALA990317 | B | Displacement of [3H]ryanodine from Ry1R/FKBP12 receptor complex in rabbit sarcoplasmic reticulum | Oryctolagus cuniculus | 5 | single protein format | Scientific Literature | ||
12. | ALA1112436 | F | Antitrypanosomal activity against Trypanosoma brucei brucei 221 after 48 hrs by ATP-bioluminescence assay | Trypanosoma brucei brucei | 9 | organism-based format | Scientific Literature | ||
13. | ALA1112437 | F | Cytotoxicity against human HCT116 cells after 7 days by methylene blue staining | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
14. | ALA3225493 | F | Antiproliferative activity against bFGF-treated HUVEC | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
15. | ALA3225494 | U | Selectivity index, ratio of IC50 for human KB3-1 cells to IC50 for bFGF-treated HUVEC | 10 | cell-based format | Scientific Literature | |||
16. | ALA3637317 | B | Inhibition of ACAT in human MDM cells assessed as inhibition of foam cell formation by measuring acetylated LDL-induced [3H]cholesterol ester accumulation at 5 uM after 24 hrs in presence of 0.1 mM [3H]oleate | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
17. | ALA3637318 | A | Cytotoxicity against human MDM cells at 5 uM after 24 hrs | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
18. | ALA3637319 | B | Inhibition of human ACAT1 expressed in CHO cells assessed as inhibition of [3H]cholesterol ester accumulation at 5 uM in presence of 0.1 mM [3H]oleate-conjugated BSA | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
19. | ALA3637434 | B | Inhibition of human ACAT2 expressed in CHO cells assessed as inhibition of [3H]cholesterol ester accumulation at 5 uM in presence of 0.1 mM [3H]oleate-conjugated BSA | Homo sapiens | 8 | cell-based format | Scientific Literature |