# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA869818 | B | Binding affinity to 5HT2C | Homo sapiens | 22 | single protein format | Scientific Literature | ||
2. | ALA869819 | B | Selectivity for 5HT2C over 5HT2A | Homo sapiens | 11 | protein format | Scientific Literature | ||
3. | ALA869820 | B | Selectivity for 5HT2C over 5HT2B | Homo sapiens | 11 | protein format | Scientific Literature | ||
4. | ALA869824 | F | Inhibition of 5HT2C assessed as intracellular calcium concentration | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA871013 | A | Ratio of drug level in brain against plasma measured as AUC cortex/AUC plasma at 1.2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA871017 | A | Clearance in rat at 1.2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
7. | ALA871019 | A | Half life in rat at 1.2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA870367 | A | Oral bioavailability in rat at 10.6 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA870332 | A | Clearance in dog at 1.0 mg/kg, iv | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
10. | ALA870333 | A | Half life in dog at 1.0 mg/kg, iv | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
11. | ALA870334 | A | Oral bioavailability in dog at 10.6 mg/kg, po | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
12. | ALA870335 | F | Reduction of food intake in ip dosed rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
13. | ALA870336 | F | Reduction of food intake in rat at 10 mg/kg, ip after 4 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
14. | ALA870337 | F | Reduction of food intake in rat at 20 mg/kg, ip after 24 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature |