# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA868018 | F | Negative inotropic activity in guinea pig left atrium at 1 uM | Cavia porcellus | 4 | ALA1146021 | organism-based format | Scientific Literature | |
2. | ALA866217 | F | Negative chronotropic activity in guinea pig right atrium at 100 uM | Cavia porcellus | 3 | ALA1146021 | organism-based format | Scientific Literature | |
3. | ALA867411 | F | Negative inotropic activity in guinea pig left atrium | Cavia porcellus | 23 | ALA1146021 | organism-based format | Scientific Literature | |
4. | ALA869216 | F | Vasorelaxant activity assessed as inhibition of calcium-induced contraction of potassium ion-depolarized guinea pig aortic strips at 100 uM | Cavia porcellus | 19 | ALA1146021 | organism-based format | Scientific Literature | |
5. | ALA869222 | F | Negative inotropic activity in guinea pig left ventricular papillary muscle at 500 uM | Cavia porcellus | 1 | ALA1146021 | organism-based format | Scientific Literature | |
6. | ALA869228 | F | Cardiac activity in guinea pig heart measured as decrease in left ventricular pressure at 1 uM relative to control | Cavia porcellus | 6 | ALA1146021 | organism-based format | Scientific Literature | |
7. | ALA869231 | F | Cardiac activity in guinea pig heart measured as decrease in heart rate at 1 uM by ECG relative to control | Cavia porcellus | 6 | ALA1146021 | organism-based format | Scientific Literature | |
8. | ALA869232 | F | Cardiac activity in guinea pig heart measured as decrease in coronary perfusion pressure at 1 uM relative to control | Cavia porcellus | 5 | ALA1146021 | organism-based format | Scientific Literature | |
9. | ALA869852 | F | Cardiac activity in guinea pig heart measured as prolongation of atrioventricular conduction time at 1 uM relative to control | Cavia porcellus | 6 | ALA1146021 | organism-based format | Scientific Literature | |
10. | ALA869175 | F | Antagonist activity against calcium channel assessed as inhibition of calcium-induced contraction of potassium ion-depolarized guinea pig ileum longitudinal smooth muscle at 100 uM | Cavia porcellus | 2 | ALA1146021 | organism-based format | Scientific Literature | |
11. | ALA869181 | F | Antagonist activity against calcium channel assessed as inhibition of carbachol-induced tonic contraction of guinea pig ileum longitudinal smooth muscle | Cavia porcellus | 6 | ALA1146021 | organism-based format | Scientific Literature | |
12. | ALA1011131 | F | Antiproliferative activity against human A2780 cells at 1.5 uM after 3 days by MTT assay | Homo sapiens | 1 | ALA1139365 | cell-based format | Scientific Literature | |
13. | ALA1011143 | B | Blockade of L-type calcium channel | 2 | ALA1139365 | assay format | Scientific Literature | ||
14. | ALA1011144 | F | Antiproliferative activity against human A2780 cells after 3 days by MTT assay | Homo sapiens | 24 | ALA1139365 | cell-based format | Scientific Literature | |
15. | ALA1011145 | F | Antiproliferative activity against human A2780/DX3 cells after 3 days by MTT assay | Homo sapiens | 24 | ALA1139365 | cell-based format | Scientific Literature | |
16. | ALA1011147 | B | Reversal of P-gp 170-mediated multidrug resistance in human A2780/DX3 cells assessed as reduction in doxorubicin IC50 at IC5 pretreated for 6 hrs before doxorubicin administration measured after 3 days by MTT assay | Homo sapiens | 22 | ALA1139365 | cell-based format | Scientific Literature | |
17. | ALA1011148 | B | Reversal of P-gp 170-mediated multidrug resistance in human A2780/DX3 cells assessed as reduction in doxorubicin IC50 at IC0 pretreated for 6 hrs before doxorubicin administration measured after 3 days by MTT assay | Homo sapiens | 22 | ALA1139365 | cell-based format | Scientific Literature | |
18. | ALA1011149 | B | Reversal of P-gp 170-mediated multidrug resistance in human A2780/DX3 cells assessed as increase in intracellular doxorubicin accumulation at 5 times IC5 pretreated for 2 hrs before doxorubicin administration measured after 2 hrs by flow cytometry | Homo sapiens | 23 | ALA1139365 | cell-based format | Scientific Literature | |
19. | ALA1012054 | F | Antiproliferative activity against human A2780/DX3 cells at 1.0 uM after 3 days by MTT assay | Homo sapiens | 3 | ALA1139365 | cell-based format | Scientific Literature | |
20. | ALA1009059 | F | Effect on cardiac activity in guinea pig spontaneously beating heart assessed as change in left ventricular pressure at 1 uM relative to control | Cavia porcellus | 3 | ALA1153430 | tissue-based format | Scientific Literature |