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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA869862 | Functional | Cytotoxicity against human NCI60 cell line by MTT assay | Homo sapiens | 13 | ALA1146868 | cell-based format | Scientific Literature | |
2. | ALA869863 | Functional | Inhibition of DNA transcription at 5 uM | 6 | ALA1146868 | assay format | Scientific Literature | ||
3. | ALA855894 | ADME | Uptake in human MCF7 cells at 100 uM after 24 hrs | Homo sapiens | 5 | ALA1146868 | cell-based format | Scientific Literature | |
4. | ALA855896 | Functional | Cytotoxicity against human K562 cell line after 96 hrs by MTT assay | Homo sapiens | 13 | ALA1146868 | cell-based format | Scientific Literature | |
5. | ALA1804172 | Binding | Binding affinity to calf thymus DNA assessed as change in melting temperature at 5 uM at pH 7 after 4 hrs by thermal denaturation assay | Bos taurus | 2 | ALA1799996 | nucleic acid format | Scientific Literature | |
6. | ALA1804173 | Binding | Binding affinity to calf thymus DNA assessed as change in melting temperature at 5 uM at pH 7 after 18 hrs by thermal denaturation assay | Bos taurus | 2 | ALA1799996 | nucleic acid format | Scientific Literature | |
7. | ALA1804174 | Binding | Binding affinity to ICB1 site of human topoisomerase 2alpha promoter after 17 hrs by DNase 1 footprinting assay | Homo sapiens | 1 | ALA1799996 | nucleic acid format | Scientific Literature | |
8. | ALA1804175 | Binding | Binding affinity to ICB2 site of human topoisomerase 2alpha promoter after 17 hrs by DNase 1 footprinting assay | Homo sapiens | 1 | ALA1799996 | nucleic acid format | Scientific Literature | |
9. | ALA1804176 | Functional | Cytotoxicity against human NCI60 cells | Homo sapiens | 2 | ALA1799996 | cell-based format | Scientific Literature | |
10. | ALA2149769 | Binding | Binding affinity to 5'-TATA-AGA-TTT-TCT-TATA at 200 uM by HPLC/MS analysis | 1 | ALA2146450 | nucleic acid format | Scientific Literature | ||
11. | ALA2149770 | Binding | Binding affinity to 5'-TATA-TGT-TTT-ACA-TATA at 200 uM by HPLC/MS analysis | 1 | ALA2146450 | nucleic acid format | Scientific Literature | ||
12. | ALA2150219 | Binding | Binding affinity to 5'-TATA-AGT-TTT-ACT-TATA at 200 uM by HPLC/MS analysis | 1 | ALA2146450 | nucleic acid format | Scientific Literature | ||
13. | ALA2150220 | Binding | Binding affinity to 5'-TATA-TGA-TTT-TCA-TATA at 200 uM by HPLC/MS analysis | 1 | ALA2146450 | nucleic acid format | Scientific Literature | ||
14. | ALA2150221 | Binding | Binding affinity to 5'-AGA-TATA-TTT-TATA-TCT at 200 uM by HPLC/MS analysis | 1 | ALA2146450 | nucleic acid format | Scientific Literature | ||
15. | ALA2150222 | Binding | Binding affinity to 5'-TGT-TATA-TTT-TATA-ACA at 200 uM by HPLC/MS analysis | 1 | ALA2146450 | nucleic acid format | Scientific Literature | ||
16. | ALA2150223 | Binding | Binding affinity to 5'-AGT-TATA-TTT-TATA-ACT at 200 uM by HPLC/MS analysis | 1 | ALA2146450 | nucleic acid format | Scientific Literature | ||
17. | ALA2150224 | Binding | Binding affinity to 5'-TGA-TATA-TTT-TATA-TCA at 200 uM by HPLC/MS analysis | 1 | ALA2146450 | nucleic acid format | Scientific Literature | ||
18. | ALA2330264 | Binding | Binding affinity to GC-rich FAM-GCGCAGATTTTCTGCGC-TAMRA DNA (unknown origin) assessed as change in melting temperature at 1 uM by FRET assay | Not specified | 11 | ALA2321778 | assay format | Scientific Literature | |
19. | ALA2330265 | Binding | Binding affinity to AT-rich FAM-TATAAGATTTTCTTATA-TAMRA DNA (unknown origin) assessed as change in melting temperature at 1 uM by FRET assay | Not specified | 11 | ALA2321778 | assay format | Scientific Literature | |
20. | ALA2330266 | Binding | Binding affinity to GC-rich GCGC-AGA-TTT-TCT-GCGC DNA (unknown origin) after 5 mins by HPLC-MS analysis (Rvb = 12 %) | Not specified | 2 | ALA2321778 | assay format | Scientific Literature |