# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA864275 | F | Inhibition of TRAP activity in RANKL-induced osteoclastogenesis in RAW 264.7 cells | Mus musculus | 10 | ALA1149350 | cell-based format | Scientific Literature | |
2. | ALA864276 | F | Antiproliferative activity against RAW 264.7 cells in RANKL-induced osteoclastogenesis | Mus musculus | 10 | ALA1149350 | cell-based format | Scientific Literature | |
3. | ALA2149726 | B | Inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 30 mins by fluorescence assay | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
4. | ALA2149727 | B | Inhibition of SARS-CoV 3CLpro expressed in Escherichia coli BL21 (DE3) using Dabcyl-KNSTLQSGLRKE-Edan as substrate after 60 mins by FRET analysis | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
5. | ALA2149728 | B | Time dependent inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate at 3 to 100 uM up to 120 mins | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
6. | ALA2149729 | B | Inhibition of SARS-CoV PLpro deubiququitination expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate by fluorescence analysis | SARS coronavirus | 5 | ALA2146458 | assay format | Scientific Literature | |
7. | ALA2149732 | B | Inhibition of chymotrypsin using N-benzoyl-L-tyrosine ethyl ester as substrate assessed as benzoyl-tyrosine production at 200 uM measured every 10 seconds for 6 mins | 2 | ALA2146458 | assay format | Scientific Literature | ||
8. | ALA2149733 | B | Inhibition of papaya papain using N-alpha-benzoyl-L-arginine-pnitroanilide as substrate at 200 uM after 5 mins | Carica papaya | 4 | ALA2146458 | single protein format | Scientific Literature | |
9. | ALA2149736 | B | Inhibition of Human immunodeficiency virus 1 protease at 200 uM preincubated for 10 mins by FRET assay | Human immunodeficiency virus 1 | 1 | ALA2146458 | single protein format | Scientific Literature | |
10. | ALA2150310 | B | Time dependent inhibition of SARS-CoV 3CLpro expressed in Escherichia coli BL21 (DE3) using Dabcyl-KNSTLQSGLRKE-Edan as substrate at 1 to 100 uM by FRET analysis | SARS coronavirus | 6 | ALA2146458 | assay format | Scientific Literature | |
11. | ALA2150311 | B | Time dependent inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate at IC50 by fluorescence assay | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
12. | ALA2150312 | B | Inhibition of SARS-CoV PLpro expressed in Escherichia coli (DE3) BL21 using Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 60 mins by fluorescence assay | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
13. | ALA2150313 | B | Inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate by fluorescence assay | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
14. | ALA2150315 | B | Non competitive inhibition of SARS-CoV 3CLpro expressed in Escherichia coli BL21 (DE3) using Dabcyl-KNSTLQSGLRKE-Edan as substrate by Dixon plot analysis | SARS coronavirus | 6 | ALA2146458 | assay format | Scientific Literature | |
15. | ALA2150316 | B | Non competitive inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate by Dixon plot analysis | SARS coronavirus | 6 | ALA2146458 | assay format | Scientific Literature | |
16. | ALA3294386 | B | Inhibition of EZH2 histone methyltransferase activity in EZH2/SUZ12/EED protein complex (unknown origin) using histone H3 peptide/S-adenosylmethionine as substrate after 2 hrs by TR-FRET assay | Homo sapiens | 7 | ALA3286358 | protein complex format | Scientific Literature |