# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA909787 | B | Inhibition of Plasmodium falciparum PFT at 50 uM | Plasmodium falciparum | 42 | protein complex format | Scientific Literature | ||
2. | ALA910873 | B | Inhibition of Plasmodium falciparum PFT at 5 uM | Plasmodium falciparum | 34 | protein complex format | Scientific Literature | ||
3. | ALA910874 | F | Inhibition of Plasmodium falciparum 3D7 growth as reduced [3H]hypoxanthine incorporation | Plasmodium falciparum | 34 | organism-based format | Scientific Literature | ||
4. | ALA910292 | F | Inhibition of Plasmodium falciparum K1 growth as reduced [3H]hypoxanthine incorporation | Plasmodium falciparum | 34 | organism-based format | Scientific Literature | ||
5. | ALA910293 | B | Inhibition of Plasmodium falciparum PFT | Plasmodium falciparum | 12 | protein complex format | Scientific Literature | ||
6. | ALA910294 | B | Inhibition of rat PFT | Rattus norvegicus | 12 | protein complex format | Scientific Literature | ||
7. | ALA910295 | B | Selectivity for inhibition of Plasmodium falciparum PFT over rat PFT | Plasmodium falciparum | 11 | protein complex format | Scientific Literature | ||
8. | ALA910296 | A | Apparent permeability in Caco-2 cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
9. | ALA910297 | A | Half life in mouse liver microsome | Mus musculus | 10 | organism-based format | Scientific Literature | ||
10. | ALA910298 | A | Half life in rat liver microsome | Rattus norvegicus | 7 | microsome format | Scientific Literature | ||
11. | ALA910302 | A | AUC in rat at 50 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
12. | ALA910303 | A | Cmax in rat at 50 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
13. | ALA910304 | A | Half life in rat at 50 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
14. | ALA910305 | A | Tmax in mouse at 50 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
15. | ALA1000384 | B | Inhibition of Plasmodium falciparum PFT at 50 nM | Plasmodium falciparum | 39 | assay format | Scientific Literature | ||
16. | ALA1000385 | B | Inhibition of Plasmodium falciparum PFT at 5 nM | Plasmodium falciparum | 35 | assay format | Scientific Literature | ||
17. | ALA1000386 | F | Antimalarial activity in Plasmodium falciparum 3D7 infected erythrocytes as [3H]hypoxanthine uptake | Plasmodium falciparum | 35 | organism-based format | Scientific Literature | ||
18. | ALA1000387 | F | Antimalarial activity in Plasmodium falciparum K1 infected erythrocytes by [3H]hypoxanthine uptake | Plasmodium falciparum | 39 | organism-based format | Scientific Literature | ||
19. | ALA1260645 | B | Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLL | Homo sapiens | 57 | protein complex format | Scientific Literature | ||
20. | ALA1260646 | B | Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLS | Homo sapiens | 57 | protein complex format | Scientific Literature |