# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA909787 | B | Inhibition of Plasmodium falciparum PFT at 50 uM | Plasmodium falciparum | 42 | ALA1137254 | protein complex format | Scientific Literature | |
2. | ALA910873 | B | Inhibition of Plasmodium falciparum PFT at 5 uM | Plasmodium falciparum | 34 | ALA1137254 | protein complex format | Scientific Literature | |
3. | ALA910874 | F | Inhibition of Plasmodium falciparum 3D7 growth as reduced [3H]hypoxanthine incorporation | Plasmodium falciparum | 34 | ALA1137254 | organism-based format | Scientific Literature | |
4. | ALA910292 | F | Inhibition of Plasmodium falciparum K1 growth as reduced [3H]hypoxanthine incorporation | Plasmodium falciparum | 34 | ALA1137254 | organism-based format | Scientific Literature | |
5. | ALA910293 | B | Inhibition of Plasmodium falciparum PFT | Plasmodium falciparum | 12 | ALA1137254 | protein complex format | Scientific Literature | |
6. | ALA910294 | B | Inhibition of rat PFT | Rattus norvegicus | 12 | ALA1137254 | protein complex format | Scientific Literature | |
7. | ALA910295 | B | Selectivity for inhibition of Plasmodium falciparum PFT over rat PFT | Plasmodium falciparum | 11 | ALA1137254 | protein complex format | Scientific Literature | |
8. | ALA910296 | A | Apparent permeability in Caco-2 cells | Homo sapiens | 10 | ALA1137254 | cell-based format | Scientific Literature | |
9. | ALA910297 | A | Half life in mouse liver microsome | Mus musculus | 10 | ALA1137254 | organism-based format | Scientific Literature | |
10. | ALA910298 | A | Half life in rat liver microsome | Rattus norvegicus | 7 | ALA1137254 | microsome format | Scientific Literature | |
11. | ALA910302 | A | AUC in rat at 50 mg/kg, po | Rattus norvegicus | 1 | ALA1137254 | organism-based format | Scientific Literature | |
12. | ALA910303 | A | Cmax in rat at 50 mg/kg, po | Rattus norvegicus | 1 | ALA1137254 | organism-based format | Scientific Literature | |
13. | ALA910304 | A | Half life in rat at 50 mg/kg, po | Rattus norvegicus | 1 | ALA1137254 | organism-based format | Scientific Literature | |
14. | ALA910305 | A | Tmax in mouse at 50 mg/kg, po | Mus musculus | 3 | ALA1137254 | organism-based format | Scientific Literature | |
15. | ALA1000384 | B | Inhibition of Plasmodium falciparum PFT at 50 nM | Plasmodium falciparum | 39 | ALA1157352 | assay format | Scientific Literature | |
16. | ALA1000385 | B | Inhibition of Plasmodium falciparum PFT at 5 nM | Plasmodium falciparum | 35 | ALA1157352 | assay format | Scientific Literature | |
17. | ALA1000386 | F | Antimalarial activity in Plasmodium falciparum 3D7 infected erythrocytes as [3H]hypoxanthine uptake | Plasmodium falciparum | 35 | ALA1157352 | organism-based format | Scientific Literature | |
18. | ALA1000387 | F | Antimalarial activity in Plasmodium falciparum K1 infected erythrocytes by [3H]hypoxanthine uptake | Plasmodium falciparum | 39 | ALA1157352 | organism-based format | Scientific Literature | |
19. | ALA1260645 | B | Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLL | Homo sapiens | 57 | ALA1255187 | protein complex format | Scientific Literature | |
20. | ALA1260646 | B | Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLS | Homo sapiens | 57 | ALA1255187 | protein complex format | Scientific Literature |