| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA908864 | B | Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 2. | ALA908865 | F | Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 3. | ALA908866 | B | Inhibition of PLA2 at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA908867 | B | Inhibition of COX1 at 10 uM | 1 | single protein format | Scientific Literature | |||
| 5. | ALA908868 | B | Inhibition of COX2 at 10 uM | 1 | single protein format | Scientific Literature | |||
| 6. | ALA908869 | B | Inhibition of 12-LO at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA908870 | B | Inhibition of 15-LO at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA908871 | B | Inhibition of DP1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA908872 | B | Inhibition of AT1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA908873 | B | Inhibition of AT2 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA908265 | B | Inhibition of mouse CRTH2 receptor | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 12. | ALA908266 | P | Aqueous solubility in PBS at pH 7.4 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 13. | ALA908267 | P | Aqueous solubility at pH 1 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 14. | ALA908268 | P | Distribution coefficient, log D at pH 7.4 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 15. | ALA908269 | A | Permeability from apical to basolateral side of Caco-2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA908270 | A | Permeability from basolateral to apical side of Caco-2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA908271 | A | Stability in rat liver S9 fraction | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA908272 | A | Stability in human liver S9 fraction | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA908273 | A | Half life in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA908274 | A | Bioavailability in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!