| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA910631 | B | Displacement of [125I]human urotensin-2 from human GPR14 transfected in CHO cells | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 2. | ALA910632 | F | Agonist activity in rat aortic ring contraction assay | Rattus norvegicus | 19 | organism-based format | Scientific Literature | ||
| 3. | ALA910633 | F | Agonist activity in rat aortic ring contraction assay relative to 1 uM phenylephrine | Rattus norvegicus | 18 | organism-based format | Scientific Literature | ||
| 4. | ALA910635 | F | Antagonist activity against 1 uM human urotensin-2-induced contraction of rat aortic ring | Rattus norvegicus | 18 | tissue-based format | Scientific Literature | ||
| 5. | ALA1167035 | F | Agonist activity at rat urotensin 2 receptor expressed in CHO cells assessed as calcium mobilization by FLIPR | Rattus norvegicus | 24 | cell-based format | Scientific Literature | ||
| 6. | ALA3366481 | B | Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 7. | ALA3366482 | B | Agonist activity at UT receptor in rat aorta assessed as contraction | Rattus norvegicus | 18 | tissue-based format | Scientific Literature | ||
| 8. | ALA3366483 | B | Agonist activity at UT receptor in rat aorta assessed as contraction relative to urotensin-2 | Rattus norvegicus | 18 | tissue-based format | Scientific Literature | ||
| 9. | ALA3366484 | B | Competitive antagonist activity at UT receptor in rat aorta assessed as effect on urotensin-2-induced contraction | Rattus norvegicus | 18 | tissue-based format | Scientific Literature | ||
| 10. | ALA3366850 | A | Stability in 25% fetal calf serum assessed as parent compound remaining at 80 uM at 37 degC after 16 hrs by RP-HPLC-UV based detection assay | Bos taurus | 4 | assay format | Scientific Literature | ||
| 11. | ALA4370024 | B | Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counting assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 12. | ALA4370025 | B | Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced contraction | Rattus norvegicus | 14 | single protein format | Scientific Literature | ||
| 13. | ALA4370027 | B | Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to urotensin-2 | Rattus norvegicus | 13 | single protein format | Scientific Literature | ||
| 14. | ALA4370028 | B | Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as induction of Gq activation measured for 5 mins by luminescence detection based BRET assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 15. | ALA4370029 | B | Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as induction of Gq activation measured for 5 mins by luminescence detection based BRET assay relative to URP | Homo sapiens | 11 | cell-based format | Scientific Literature |
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