# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA912250 | B | Inhibition of human recombinant ROCK1 expressed in Sf9 cells at 10 mM | Homo sapiens | 9 | ALA1139217 | cell-based format | Scientific Literature | |
2. | ALA912246 | F | Dilatory activity against phenylephrine-induced contraction of Sprague-Dawley rat thoracic aorta | Rattus norvegicus | 9 | ALA1139217 | tissue-based format | Scientific Literature | |
3. | ALA911039 | B | Inhibition of RSK1 | Homo sapiens | 9 | ALA1139217 | single protein format | Scientific Literature | |
4. | ALA913368 | B | Inhibition of p70S6K | Homo sapiens | 9 | ALA1139217 | single protein format | Scientific Literature | |
5. | ALA853717 | A | Cmax in Sprague-Dawley rat at 1.7 mg/kg, iv | Rattus norvegicus | 1 | ALA1139217 | organism-based format | Scientific Literature | |
6. | ALA853719 | A | Half life in Sprague-Dawley rat at 1.7 mg/kg | Rattus norvegicus | 1 | ALA1139217 | organism-based format | Scientific Literature | |
7. | ALA853721 | A | Clearance in Sprague-Dawley rat at 1.7 mg/kg | Rattus norvegicus | 1 | ALA1139217 | organism-based format | Scientific Literature | |
8. | ALA853723 | A | Volume of distribution in Sprague-Dawley rat at 1.7 mg/kg | Rattus norvegicus | 1 | ALA1139217 | organism-based format | Scientific Literature | |
9. | ALA853725 | A | Oral bioavailability in Sprague-Dawley rat at 1.7 mg/kg, po | Rattus norvegicus | 1 | ALA1139217 | organism-based format | Scientific Literature | |
10. | ALA1961874 | B | GSK_PKIS: AKT1 mean inhibition at 0.1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set | ||
11. | ALA1961875 | B | GSK_PKIS: AKT1 mean inhibition at 1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set | ||
12. | ALA1961876 | B | GSK_PKIS: AKT2 mean inhibition at 0.1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set | ||
13. | ALA1961877 | B | GSK_PKIS: AKT2 mean inhibition at 1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set | ||
14. | ALA1961878 | B | GSK_PKIS: AKT3 mean inhibition at 0.1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set | ||
15. | ALA1961879 | B | GSK_PKIS: AKT3 mean inhibition at 1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set | ||
16. | ALA1961880 | B | GSK_PKIS: GRK6 mean inhibition at 0.1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set | ||
17. | ALA1961881 | B | GSK_PKIS: GRK6 mean inhibition at 1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set | ||
18. | ALA1961882 | B | GSK_PKIS: GRK7 mean inhibition at 0.1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set | ||
19. | ALA1961883 | B | GSK_PKIS: GRK7 mean inhibition at 1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set | ||
20. | ALA1961884 | B | GSK_PKIS: MRCKA mean inhibition at 0.1 uM [Nanosyn] | 366 | ALA1961873 | single protein format | GSK Published Kinase Inhibitor Set |