# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA913665 | B | Inhibition of human Cathepsin K | Homo sapiens | 8 | ALA1146175 | single protein format | Scientific Literature | |
2. | ALA913668 | A | Cytotoxicity against A549 cells | Homo sapiens | 5 | ALA1146175 | cell-based format | Scientific Literature | |
3. | ALA913669 | A | Cytotoxicity against BGC823 cells | Homo sapiens | 5 | ALA1146175 | cell-based format | Scientific Literature | |
4. | ALA913670 | A | Cytotoxicity against SGC7901 cells | Homo sapiens | 5 | ALA1146175 | cell-based format | Scientific Literature | |
5. | ALA913671 | A | Cytotoxicity against DU145 cells | Homo sapiens | 5 | ALA1146175 | cell-based format | Scientific Literature | |
6. | ALA913672 | A | Cytotoxicity against MDA-MB-231 cells | Homo sapiens | 5 | ALA1146175 | cell-based format | Scientific Literature | |
7. | ALA913673 | A | Cytotoxicity against HT29 cells | Homo sapiens | 5 | ALA1146175 | cell-based format | Scientific Literature | |
8. | ALA913674 | A | Cytotoxicity against BEL-7402 cells | Homo sapiens | 5 | ALA1146175 | cell-based format | Scientific Literature | |
9. | ALA913675 | A | Cytotoxicity against MCF7 cells | Homo sapiens | 5 | ALA1146175 | cell-based format | Scientific Literature | |
10. | ALA913676 | A | Cytotoxicity against B16 cells | Mus musculus | 5 | ALA1146175 | cell-based format | Scientific Literature | |
11. | ALA996460 | F | Growth inhibition of human OVCAR-3 cells upto 10 ug/ml after 48 hrs | Homo sapiens | 4 | ALA1145708 | cell-based format | Scientific Literature | |
12. | ALA1211753 | B | Inhibition of BACE1 after 60 mins by FRET assay | 21 | ALA1208740 | single protein format | Scientific Literature | ||
13. | ALA3404454 | F | Growth inhibition of human PC3 cells by colorimetric MTT assay | Homo sapiens | 15 | ALA3399964 | cell-based format | Scientific Literature | |
14. | ALA3592586 | F | Neuroprotective activity against 0.1 uM amyloid beta 42-induced toxicity in rat PC12 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | Rattus norvegicus | 24 | ALA3588767 | cell-based format | Scientific Literature | |
15. | ALA4138488 | B | Inhibition of full-length GST-fused human CBS using cysteine/homocysteine as substrate assessed as decrease in H2S production preincubated for 3 mins in presence of homocysteine and lead nitrate followed by cysteine addition | Homo sapiens | 12 | ALA4138050 | single protein format | Scientific Literature | |
16. | ALA4138489 | B | Inhibition of N-terminal His-tagged CSE extracted from human HepG2 cells expressed in Escherichia coli BL21 (DE3) using cysteine as substrate assessed as decrease in H2S production preincubated for 3 mins in presence of lead nitrate followed by cysteine addition | Homo sapiens | 9 | ALA4138050 | assay format | Scientific Literature | |
17. | ALA4138491 | B | Reversible inhibition of full-length GST-fused human CBS using cysteine/homocysteine as substrate assessed as decrease in H2S production at 100 uM preincubated for 1 hr followed by ultrafiltration for 5 times | Homo sapiens | 11 | ALA4138050 | single protein format | Scientific Literature | |
18. | ALA4138492 | F | Antiproliferative activity against human HT-29 cells assessed as decrease in cell viability after 24 hrs by CCK8 assay | Homo sapiens | 7 | ALA4138050 | cell-based format | Scientific Literature | |
19. | ALA4138493 | A | Antiproliferative activity against human NCM356 cells assessed as decrease in cell viability after 24 hrs by CCK8 assay | Homo sapiens | 3 | ALA4138050 | cell-based format | Scientific Literature | |
20. | ALA4138494 | T | Selectivity index, ratio of IC50 for human NCM356 cells to IC50 for human HT-29 cells | Homo sapiens | 2 | ALA4138050 | assay format | Scientific Literature |