| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA684310 | B | Inhibition constant of compound against binding of Yeast Glyoxalase I | Saccharomyces cerevisiae | 41 | ALA1124156 | single protein format | Scientific Literature | |
| 2. | ALA857390 | B | Compound was evaluated for inhibition of Saccharomyces cerevisiae glyoxalase-I, activity i determined with 0.5 mM substrate | Saccharomyces cerevisiae | 2 | ALA1131657 | single protein format | Scientific Literature | |
| 3. | ALA686108 | B | Compound was evaluated for inhibition of Saccharomyces cerevisiae glyoxalase-I by using enzymatic assay at each of 6 substrate concentrations between 0.1 mM and 2.0 mM | Saccharomyces cerevisiae | 3 | ALA1131657 | single protein format | Scientific Literature | |
| 4. | ALA702154 | F | Tested for cytotoxicity in human K562 cells | Homo sapiens | 22 | ALA1132941 | cell-based format | Scientific Literature | |
| 5. | ALA711916 | F | Evaluated for antiparasitic activity against Leishmania donovani; NA is Not active. | Leishmania donovani | 10 | ALA1132941 | organism-based format | Scientific Literature | |
| 6. | ALA815844 | F | Evaluated for antiparasitic activity against Trypanosoma cruzi amastigotes; NA is Not active. | Trypanosoma cruzi | 10 | ALA1132941 | organism-based format | Scientific Literature | |
| 7. | ALA814527 | F | Evaluated for antiparasitic activity against brucei trypomastigotes | Trypanosoma brucei | 14 | ALA1132941 | organism-based format | Scientific Literature | |
| 8. | ALA821876 | B | Ability to inhibit yeast glyoxalase I enzyme in 0.05 M phosphate buffer, pH 6.6, 30 degree C | Saccharomyces cerevisiae | 2 | ALA1132077 | single protein format | Scientific Literature | |
| 9. | ALA911359 | A | Stability against equine kidney gamma-glutamyltranspeptidase mediated breakdown at pH 8.4 after 15 mins | 2 | ALA1146153 | tissue-based format | Scientific Literature | ||
| 10. | ALA967534 | B | Inhibition of human recombinant His-tagged Glyoxalase 1 expressed in Sf21-Baculovirus system | Homo sapiens | 6 | ALA1157146 | assay format | Scientific Literature | |
| 11. | ALA1030416 | B | Inhibition of yeast glyoxalase 1 | Saccharomyces cerevisiae | 8 | ALA1158485 | single protein format | Scientific Literature | |
| 12. | ALA1251073 | B | Inhibition of human recombinant glyoxalase 1 assessed as S-D-lactoylglutathione after 15 mins by spectrophotometric analysis | Homo sapiens | 4 | ALA1250526 | single protein format | Scientific Literature | |
| 13. | ALA1913551 | B | Inhibition of recombinant human His-tagged glyoxalase 1 expressed in Escherichia coli BL21 assessed as formation of S-D-lactoylglutathione after 5 mins by spectrophotometric method | Homo sapiens | 5 | ALA1909515 | assay format | Scientific Literature | |
| 14. | ALA2212266 | B | Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's method | Homo sapiens | 18 | ALA2203256 | assay format | Scientific Literature | |
| 15. | ALA3285009 | B | Competitive inhibition of yeast glyoxalase 1 assessed as inhibition of product formation by double reciprocal plot method | Saccharomyces cerevisiae | 2 | ALA3272127 | assay format | Scientific Literature | |
| 16. | ALA3285011 | B | Binding affinity to active site of yeast glyoxalase 1 using hemimercaptal as substrate at 0.005 to 0.015 mM in presence of free glutathione | Saccharomyces cerevisiae | 1 | ALA3272127 | assay format | Scientific Literature | |
| 17. | ALA3300061 | B | Inhibition of GLO1 (unknown origin) | Homo sapiens | 1 | ALA3297683 | single protein format | Scientific Literature | |
| 18. | ALA4404011 | B | Inhibition of Glyoxalase-1 (unknown origin) using GSH and MGO as substrates preincubated with substrates for 6 mins followed by enzyme addition by spectrophotometric method | Homo sapiens | 1 | ALA4402553 | single protein format | Scientific Literature |
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