# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA751111 | F | Antagonist activity against recombinant rat receptor P2X purinoceptor 2 (P2X2) at 10 uM, expressed in Xenopus oocytes | 7 | ALA1135773 | cell-based format | Scientific Literature | ||
2. | ALA750982 | F | Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4) | 8 | ALA1135773 | assay format | Scientific Literature | ||
3. | ALA751765 | F | Evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 2 (P2Y2) | 12 | ALA1135773 | assay format | Scientific Literature | ||
4. | ALA759188 | F | Evaluated for antagonist activity agonist phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytes | Meleagris gallopavo | 1 | ALA1135773 | assay format | Scientific Literature | |
5. | ALA755047 | F | Agonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11) | 10 | ALA1135773 | assay format | Scientific Literature | ||
6. | ALA756289 | F | Antagonist activity against phospholipase C coupled rat P2Y purinoceptor 12 (P2Y12) | 12 | ALA1135773 | assay format | Scientific Literature | ||
7. | ALA756887 | F | The compound was evaluated for antagonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 4 (P2Y4) | 1 | ALA1135773 | assay format | Scientific Literature | ||
8. | ALA757046 | F | Evaluated for antagonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 6 (P2Y6) | 1 | ALA1135773 | assay format | Scientific Literature | ||
9. | ALA911342 | B | Inhibition of rat recombinant NTPDase1 expressed in CHO cells | Rattus norvegicus | 3 | ALA1146151 | cell-based format | Scientific Literature | |
10. | ALA911343 | B | Inhibition of rat recombinant NTPDase2 expressed in CHO cells | Rattus norvegicus | 3 | ALA1146151 | cell-based format | Scientific Literature | |
11. | ALA911344 | B | Inhibition of rat recombinant NTPDase3 expressed in CHO cells | Rattus norvegicus | 3 | ALA1146151 | cell-based format | Scientific Literature | |
12. | ALA911346 | P | Stability at pH 7.6 at 10 uM | 3 | ALA1146151 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA929975 | F | Antagonist activity at mouse P2Y2 receptor in mouse NG108-15 cells assessed as inhibition of UTP-induced calcium mobilization | Mus musculus | 20 | ALA1141609 | cell-based format | Scientific Literature | |
14. | ALA929976 | F | Antagonist activity at human recombinant P2Y2 receptor in 1321N1 cells assessed as inhibition of UTP-induced calcium mobilization | Homo sapiens | 20 | ALA1141609 | cell-based format | Scientific Literature | |
15. | ALA971529 | F | Antagonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as inhibition of UTP-induced calcium mobilization | Homo sapiens | 2 | ALA1138525 | cell-based format | Scientific Literature | |
16. | ALA971530 | F | Antagonist activity at N-terminal HA epitope-tagged wild type 3 human P2Y2 receptor expressed in human 1321N1 cells assessed as inhibition of UTP-induced calcium mobilization | Homo sapiens | 2 | ALA1138525 | cell-based format | Scientific Literature | |
17. | ALA971533 | F | Antagonist activity at N-terminal HA epitope-tagged human P2Y2 receptor Y114A mutant expressed in human 1321N1 cells assessed as inhibition of UTP-induced calcium mobilization | Homo sapiens | 2 | ALA1138525 | cell-based format | Scientific Literature | |
18. | ALA974436 | F | Antagonist activity at N-terminal HA epitope-tagged wild type 4 human P2Y2 receptor expressed in human 1321N1 cells assessed as inhibition of UTP-induced calcium mobilization | Homo sapiens | 2 | ALA1138525 | cell-based format | Scientific Literature | |
19. | ALA974438 | B | Ratio of IC50 for N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant to IC50 for wild type 3 human P2Y2 receptor | Homo sapiens | 2 | ALA1138525 | single protein format | Scientific Literature | |
20. | ALA974456 | F | Antagonist activity at N-terminal HA epitope-tagged human P2Y2 receptor R177A_R180A double mutant expressed in human 1321N1 cells assessed as inhibition of UTP-induced calcium mobilization | Homo sapiens | 2 | ALA1138525 | cell-based format | Scientific Literature |