| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA919379 | B | Inhibition of Cryptosporidium hominis DHFR-TS expressed in Escherichia coli | Cryptosporidium hominis | 16 | ALA1142238 | assay format | Scientific Literature | |
| 2. | ALA919380 | B | Inhibition of Toxoplasma gondii DHFR-TS | Toxoplasma gondii | 16 | ALA1142238 | single protein format | Scientific Literature | |
| 3. | ALA919383 | B | Ligand efficiency at Cryptosporidium hominis DHFR-TS relative to TMP | Cryptosporidium hominis | 3 | ALA1142238 | assay format | Scientific Literature | |
| 4. | ALA919384 | B | Ligand efficiency at Toxoplasma gondii DHFR-TS relative to TMP | Toxoplasma gondii | 3 | ALA1142238 | single protein format | Scientific Literature | |
| 5. | ALA999459 | B | Inhibition of Bacillus anthracis recombinant DHFR expressed in mouse M15 cells assessed as rate of enzyme-dependent NADPH oxidation | Bacillus anthracis | 16 | ALA1140220 | cell-based format | Scientific Literature | |
| 6. | ALA999460 | B | Inhibition of human DHFR assessed as rate of enzyme-dependent NADPH oxidation | Homo sapiens | 16 | ALA1140220 | single protein format | Scientific Literature | |
| 7. | ALA999461 | B | Selectivity ratio of IC50 for human DHFR to IC50 for Bacillus anthracis recombinant DHFR | 16 | ALA1140220 | assay format | Scientific Literature | ||
| 8. | ALA1044821 | B | Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrate | Candida albicans | 82 | ALA1154109 | assay format | Scientific Literature | |
| 9. | ALA1044822 | B | Inhibition of human DHFR assessed as rate of NADPH consumption using dihydrofolate as substrate | Homo sapiens | 36 | ALA1154109 | single protein format | Scientific Literature | |
| 10. | ALA1044823 | B | Selectivity index, ratio of IC50 for human DHFR to IC50 for Candida albicans DHFR | 36 | ALA1154109 | assay format | Scientific Literature | ||
| 11. | ALA1044824 | F | Antifungal activity against Candida albicans by alamar blue assay | Candida albicans | 35 | ALA1154109 | organism-based format | Scientific Literature | |
| 12. | ALA1044825 | A | Cytotoxicity against human MCF10A cells after 4 hrs by alamar blue assay | Homo sapiens | 35 | ALA1154109 | cell-based format | Scientific Literature | |
| 13. | ALA3227822 | B | Inhibition of Candida albicans DHFR | Candida albicans | 3 | ALA3217444 | single protein format | Scientific Literature | |
| 14. | ALA3227823 | B | Inhibition of Candida glabrata DHFR | Nakaseomyces glabratus | 3 | ALA3217444 | assay format | Scientific Literature | |
| 15. | ALA3226050 | F | Antifungal activity against Candida albicans | Candida albicans | 2 | ALA3217444 | organism-based format | Scientific Literature | |
| 16. | ALA3226051 | F | Antifungal activity against Candida glabrata | Nakaseomyces glabratus | 2 | ALA3217444 | organism-based format | Scientific Literature |
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