# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA919884 | B | Inhibition of human recombinant GST-PRMT1 expressed in BL21 cells | Homo sapiens | 25 | ALA1142956 | cell-based format | Scientific Literature | |
2. | ALA919885 | B | Inhibition of Aspergillus nidulans recombinant GST-RmtA expressed in BL21 cells | Aspergillus nidulans | 25 | ALA1142956 | cell-based format | Scientific Literature | |
3. | ALA1646040 | F | Inhibition of HMGB1 release in human staurosporine-induced HeLaS3 cells at 100 uM treated 1 hr before staurosporine challenge measured after 24 hrs by Western blotting | Homo sapiens | 3 | ALA1641435 | cell-based format | Scientific Literature | |
4. | ALA1646041 | B | Inhibition of human recombinant DNase gamma expressed in Rosetta DE3 cells assessed as increase in acid soluble DNA after 30 mins | Homo sapiens | 3 | ALA1641435 | cell-based format | Scientific Literature | |
5. | ALA1646042 | B | Inhibition of DNase gamma-mediated nucleosomal DNA fragmentation expressed in human staurosporine-induced HeLaS3 cells treated 1 hr before staurosporine challenge measured after 24 hrs by Western blotting | 1 | ALA1641435 | cell-based format | Scientific Literature | ||
6. | ALA1646043 | B | Inhibition of DNase gamma-mediated nucleosomal DNA fragmentation expressed in human staurosporine-induced HeLaS3 cells at 30 uM treated 1 hr before staurosporine challenge measured after 24 hrs by Western blotting | 1 | ALA1641435 | cell-based format | Scientific Literature | ||
7. | ALA1646044 | B | Inhibition of DNase gamma-mediated HMGB1 release expressed in human staurosporine-induced HeLaS3 cells treated 1 hr before staurosporine challenge measured after 24 hrs by Western blotting | 1 | ALA1641435 | cell-based format | Scientific Literature | ||
8. | ALA3368169 | B | Inhibition of DNase gamma (unknown origin) transfected in HeLa S3 cells | Homo sapiens | 1 | ALA3352007 | cell-based format | Scientific Literature | |
9. | ALA3368170 | B | Inhibition of DNase 1 (unknown origin) | Homo sapiens | 1 | ALA3352007 | single protein format | Scientific Literature | |
10. | ALA3855157 | B | Inhibition of GST-tagged Caenorhabditis elegans CRN-4 exonuclease activity expressed in Escherichia coli BL21 (DE3) pLysS preincubated for 10 mins followed by [gamma-32P]ATP labelled 11-nucleotide ssRNA substrate addition for 30 mins by PAGE based autoradiography | Caenorhabditis elegans | 9 | ALA3853325 | assay format | Scientific Literature | |
11. | ALA3855158 | B | Inhibition of N-terminal His-tagged recombinant Escherichia coli K-12 RNase T exonuclease activity expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL preincubated for 10 mins followed by [gamma-32P]ATP labelled 11-nucleotide ssDNA substrate addition for 40 mins by PAGE based autoradiography | Escherichia coli K-12 | 9 | ALA3853325 | assay format | Scientific Literature | |
12. | ALA3855159 | B | Inhibition of 5'-[gamma-32P]ATP-labelled 11-nucleotide ssRNA binding to Caenorhabditis elegans GST-tagged CRN-4 expressed in Escherichia coli BL21 (DE3) pLysS at 1 mM preincubated for 10 mins followed by substrate addition measured after 20 mins by TBE gel electrophoresis mobility shift assay | Caenorhabditis elegans | 8 | ALA3853325 | assay format | Scientific Literature | |
13. | ALA3855161 | B | Inhibition of 5'-[gamma-32P]ATP-labelled 11-nucleotide ssDNA binding to recombinant Escherichia coli K-12 N-terminal His-tagged RNase T expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL at 1 mM preincubated for 10 mins followed by substrate addition measured after 20 mins by TBE gel electrophoresis mobility shift assay | Escherichia coli K-12 | 9 | ALA3853325 | assay format | Scientific Literature | |
14. | ALA3855162 | B | Inhibition of Lassa virus N-terminal His-tagged NP exonuclease domain (342 to 569 residues) expressed in Escherichia coli Tuner (DE3) using FAM-labeled 20-nucleotide ssRNA preincubated for 10 mins followed by substrate addition measured after 60 mins by PAGE based autoradiography | Mammarenavirus lassaense | 9 | ALA3853325 | assay format | Scientific Literature | |
15. | ALA3855163 | B | Inhibition of Lassa virus N-terminal His-tagged NP exonuclease domain (342 to 569 residues) expressed in Escherichia coli Tuner (DE3) using 3'-overhang 4-nucleotide stem-loop RNA preincubated for 10 mins followed by substrate addition measured after 60 mins by PAGE based autoradiography | Mammarenavirus lassaense | 9 | ALA3853325 | assay format | Scientific Literature |