# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA691543 | Functional | Compound was evaluated for inhibition of Herpes simplex virus -1 (HSV-1) - induced cytopathic effect in HUT78 cells (in vitro) | Homo sapiens | 2 | ALA1125544 | cell-based format | Scientific Literature | |
2. | ALA709950 | Functional | Compound was evaluated for inhibition of HIV-1- induced cytopathic effect in MT-4 cells (in vitro) | Homo sapiens | 1 | ALA1125544 | cell-based format | Scientific Literature | |
3. | ALA919512 | ADME | Cytotoxicity against human 41M cells after 96 hrs by MTT assay | Homo sapiens | 5 | ALA1142947 | cell-based format | Scientific Literature | |
4. | ALA919513 | ADME | Cytotoxicity against human SKBR3 cells after 96 hrs by MTT assay | Homo sapiens | 5 | ALA1142947 | cell-based format | Scientific Literature | |
5. | ALA919511 | Binding | Effect on mouse ribonucleotide reductase R2 protein measured by tyrosyl radical concentration in aerobic condition at 3 mM, 298 K after 1 min | Mus musculus | 1 | ALA1142947 | single protein format | Scientific Literature | |
6. | ALA919514 | Binding | Effect on mouse ribonucleotide reductase R2 protein measured by tyrosyl radical concentration in aerobic condition at 3 mM, 298 K after 15 mins | Mus musculus | 1 | ALA1142947 | single protein format | Scientific Literature | |
7. | ALA918947 | Binding | Effect on mouse ribonucleotide reductase R2 protein measured by tyrosyl radical concentration in aerobic condition at 3 mM, 298 K after 1005 mins | Mus musculus | 1 | ALA1142947 | single protein format | Scientific Literature | |
8. | ALA918948 | Binding | Effect on mouse ribonucleotide reductase R2 protein measured by tyrosyl radical concentration in anaerobic condition at 3 mM, 298 K after 1 min | Mus musculus | 1 | ALA1142947 | single protein format | Scientific Literature | |
9. | ALA918949 | Binding | Effect on mouse ribonucleotide reductase R2 protein measured by tyrosyl radical concentration in anaerobic condition at 3 mM, 298 K after 15 mins | Mus musculus | 1 | ALA1142947 | single protein format | Scientific Literature | |
10. | ALA918950 | Binding | Effect on mouse ribonucleotide reductase R2 protein measured by tyrosyl radical concentration in anaerobic condition at 3 mM, 298 K after 1005 mins | Mus musculus | 1 | ALA1142947 | single protein format | Scientific Literature | |
11. | ALA766232 | Functional | Increased mean survival time in drug-sensitive Plasmodium berghei infected mice (Mus musculus) at 160 mg/kg; toxic in 5 of 5 | Plasmodium berghei | 4 | ALA1122447 | organism-based format | Scientific Literature | |
12. | ALA762608 | Functional | Increased mean survival time in drug-sensitive Plasmodium berghei infected mice (Mus musculus) at 40 mg/kg dose | Plasmodium berghei | 13 | ALA1122447 | organism-based format | Scientific Literature | |
13. | ALA760317 | Functional | Increased mean survival time in drug-sensitive Plasmodium berghei infected mice (Mus musculus) at 640 mg/kg; toxic in 5 of 5 | Plasmodium berghei | 4 | ALA1122447 | organism-based format | Scientific Literature | |
14. | ALA957058 | Functional | Antiproliferative activity against human SK-N-MC cells after 72 hrs by MTT assay | Homo sapiens | 10 | ALA1140951 | cell-based format | Scientific Literature | |
15. | ALA957059 | Physicochemical | Octanol-water partition coefficient, log P of the compound | 8 | ALA1140951 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA957060 | Functional | Induction of iron mobilization in 59Fe]transferrin labeled human SK-N-MC cells assessed as iron release at 25 uM after 3 hrs by gamma scintillation counter | Homo sapiens | 9 | ALA1140951 | cell-based format | Scientific Literature | |
17. | ALA957062 | Binding | Reduction of cellular iron uptake from 59Fe]transferrin in human SK-N-MC cells at 25 uM after 3 hrs relative to control | Homo sapiens | 9 | ALA1140951 | cell-based format | Scientific Literature | |
18. | ALA957063 | Binding | Induction of iron removal from 59Fe]transferrin assessed as iron release after 3 hrs relative to control | 12 | ALA1140951 | single protein format | Scientific Literature | ||
19. | ALA1963976 | Functional | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | 27,593 | ALA1201862 | cell-based format | PubChem BioAssays | ||
20. | ALA1963981 | Functional | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | 41,327 | ALA1201862 | cell-based format | PubChem BioAssays |