| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA918965 | B | Displacement of [125I]DOI from human recombinant 5HT2A expressed in HEK293E cells | Homo sapiens | 48 | ALA1142951 | cell-based format | Scientific Literature | |
| 2. | ALA918966 | B | Displacement of [3H]LSD from human recombinant 5HT2B expressed in HEK293E cells | Homo sapiens | 48 | ALA1142951 | cell-based format | Scientific Literature | |
| 3. | ALA918967 | B | Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cells | Homo sapiens | 48 | ALA1142951 | cell-based format | Scientific Literature | |
| 4. | ALA918968 | F | Activity at human 5HT2A expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assay | Homo sapiens | 48 | ALA1142951 | cell-based format | Scientific Literature | |
| 5. | ALA918969 | F | Activity at human 5HT2B expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assay | Homo sapiens | 48 | ALA1142951 | cell-based format | Scientific Literature | |
| 6. | ALA918970 | F | Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assay | Homo sapiens | 48 | ALA1142951 | cell-based format | Scientific Literature | |
| 7. | ALA918972 | F | Activity at human 5HT2B expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assay relative to serotonin | Homo sapiens | 47 | ALA1142951 | cell-based format | Scientific Literature | |
| 8. | ALA918973 | F | Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assay relative to serotonin | Homo sapiens | 47 | ALA1142951 | cell-based format | Scientific Literature | |
| 9. | ALA918974 | B | Selectivity for human 5HT2C over human 5HT2B | Homo sapiens | 5 | ALA1142951 | protein format | Scientific Literature | |
| 10. | ALA918975 | B | Selectivity for human 5HT2C over human 5HT2A | Homo sapiens | 5 | ALA1142951 | protein format | Scientific Literature | |
| 11. | ALA918976 | A | Tmax in Sprague-Dawley rat at 8.8 mg/kg, po | Rattus norvegicus | 1 | ALA1142951 | organism-based format | Scientific Literature | |
| 12. | ALA918977 | A | Cmax in Sprague-Dawley rat at 8.8 mg/kg, po | Rattus norvegicus | 1 | ALA1142951 | organism-based format | Scientific Literature | |
| 13. | ALA918978 | A | Half life in Sprague-Dawley rat at 8.8 mg/kg, po | Rattus norvegicus | 1 | ALA1142951 | organism-based format | Scientific Literature | |
| 14. | ALA920380 | A | AUC (total) in Sprague-Dawley rat at 8.8 mg/kg, po | Rattus norvegicus | 1 | ALA1142951 | organism-based format | Scientific Literature | |
| 15. | ALA920381 | A | Bioavailability in Sprague-Dawley rat at 8.8 mg/kg, po | Rattus norvegicus | 1 | ALA1142951 | organism-based format | Scientific Literature | |
| 16. | ALA920382 | A | Plasma clearance in Sprague-Dawley rat at 4.4 mg/kg, iv | Rattus norvegicus | 1 | ALA1142951 | organism-based format | Scientific Literature | |
| 17. | ALA920383 | A | Volume of distribution of steady state in Sprague-Dawley rat at 4.4 mg/kg, iv | Rattus norvegicus | 1 | ALA1142951 | organism-based format | Scientific Literature | |
| 18. | ALA920384 | A | Permeability in Caco-2 cells | Homo sapiens | 1 | ALA1142951 | cell-based format | Scientific Literature | |
| 19. | ALA920385 | A | Plasma Protein binding | Homo sapiens | 1 | ALA1142951 | cell-free format | Scientific Literature | |
| 20. | ALA920386 | A | Unbound (%) ligand in human serum | Homo sapiens | 1 | ALA1142951 | cell-free format | Scientific Literature |
The page will load shortly, Thanks for your patience!