# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA920408 | B | Stabilization of Pu27 oligomer by inducing G-quadruplex formation assessed as inhibition of hybridization with Pu27rev by PCR stop assay | 10 | assay format | Scientific Literature | |||
2. | ALA920409 | B | Inhibition of Pu27 oligomer hybridization with Pu27rev at 6 uM by PCR stop assay | 1 | assay format | Scientific Literature | |||
3. | ALA904234 | B | Inhibition of Pu27-13, 14 oligomer hybridization with Pu27rev at 36 uM by PCR stop assay | 10 | assay format | Scientific Literature | |||
4. | ALA904235 | F | Growth inhibition in HepG2 cells after 5 days | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA904236 | F | Growth inhibition in HepG2 cells after 7 days | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA904237 | F | Inhibition of c-myc expression in HepG2 cells at 50 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA904239 | F | Inhibition of c-myc expression in CA46 cells at 10 uM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA904240 | F | Inhibition of c-myc expression in Ramos cells at 10 uM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA2182758 | B | Thermal stability of c-MYC G-quadruplex DNA assessed as change in melting temperature at DNA:compound ratio 1:1 by spectropolarimeter analysis | 16 | nucleic acid format | Scientific Literature | |||
10. | ALA2182759 | F | Cytotoxicity against human HCT116 cells after 96 hrs by MTS assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
11. | ALA2182760 | F | Cytotoxicity against human Raji cells after 96 hrs by MTS assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
12. | ALA2185352 | B | Decrease of c-MYC G-quadruplex DNA-mediated c-MYC expression in exon1 in human CA46 cells at 10 uM at 24 hrs by exon-specific assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA2185353 | B | Decrease of c-MYC G-quadruplex DNA-mediated c-MYC expression in exon1 in human CA46 cells at 10 uM at 48 hrs by exon-specific assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA2185354 | B | Decrease of c-MYC G-quadruplex DNA-mediated c-MYC expression in exon1 in human CA46 cells at 10 uM at 6 hrs by exon-specific assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA2185356 | F | Cytotoxicity against human CA46 cells after 24 hrs by MTS assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
16. | ALA5105504 | B | Thermal stabilization of c-MYC parallel G4 (Pu27) DNA (unknown origin) assessed as melting temperature by CD spectra analysis | Not specified | 5 | assay format | Scientific Literature | ||
17. | ALA5114028 | F | Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition | Homo sapiens | 5 | cell-based format | Scientific Literature |