# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615153 | Binding | Binding affinity of aminoglycoside to 16S ribosomal RNA A-site in Escherichia coli | Escherichia coli | 14 | ALA1133989 | nucleic acid format | Scientific Literature | |
2. | ALA629169 | ADME | Compound was tested for the pseudo first-order rate constants for the inhibition of the cleavage step (k2) of the hammerhead ribozyme at a concentration of 100 uM | 2 | ALA1130493 | assay format | Scientific Literature | ||
3. | ALA875121 | ADME | Compound was tested for the pseudo first-order rate constants for the inhibition of the cleavage step (k2) of the hammerhead ribozyme at a concentration of 10 uM; too active and complete inhibition is observed | 1 | ALA1130493 | assay format | Scientific Literature | ||
4. | ALA631155 | ADME | Compound was tested for the pseudo first-order rate constants for the inhibition of the cleavage step (k2) of the hammerhead ribozyme at a concentration of 1 uM; too active and complete inhibition is observed | 5 | ALA1130493 | assay format | Scientific Literature | ||
5. | ALA672250 | Functional | Concentration required for half maximum rate of enhanced [3H]DHS uptake in Escherichia coli K12 | Escherichia coli | 33 | ALA1123673 | assay format | Scientific Literature | |
6. | ALA672253 | ADME | Lethal dose required to kill 90% of the Escherichia coli K12 (ATCC 25868) cell population | Escherichia coli | 31 | ALA1123673 | assay format | Scientific Literature | |
7. | ALA670527 | ADME | Percent killing of the total Escherichia coli K12 (ATCC 25868) cells at the C50 concentration was determined. | Escherichia coli | 22 | ALA1123673 | assay format | Scientific Literature | |
8. | ALA670692 | Functional | Estimated rate of [3H]DHS uptake in Escherichia coli K12 (ATCC 25868) | Escherichia coli | 31 | ALA1123673 | assay format | Scientific Literature | |
9. | ALA699212 | Binding | Denaturation rate constant of IF2 in the presence of aminoglycoside | Staphylococcus aureus | 5 | ALA1145741 | assay format | Scientific Literature | |
10. | ALA699213 | Binding | Inhibitory activity against the displacement of Picogreen from fMet-tRNA(fMet) by the aminoglycoside | Staphylococcus aureus | 5 | ALA1145741 | assay format | Scientific Literature | |
11. | ALA699214 | Binding | Inhibitory activity of the aminoglycoside on Staphylococcus aureus IF-2 binding to fMet-tRNA(fMet) | Staphylococcus aureus | 6 | ALA1145741 | assay format | Scientific Literature | |
12. | ALA699215 | Binding | Maximal inhibition against the displacement of Picogreen from fMet-tRNA(fMet) by the aminoglycoside | Staphylococcus aureus | 5 | ALA1145741 | assay format | Scientific Literature | |
13. | ALA697161 | Binding | Maximal inhibition of the aminoglycoside on Staphylococcus aureus IF-2 binding to fMet-tRNA(fMet) | Staphylococcus aureus | 6 | ALA1145741 | assay format | Scientific Literature | |
14. | ALA847431 | Functional | Percent of interaction with wheat germ tRNA (type V) at a concentration of 35 uM | Triticum aestivum | 7 | ALA1134018 | assay format | Scientific Literature | |
15. | ALA819981 | Functional | Percent of interaction with calf thymus DNA (activated type XV) at a concentration of 35 uM | Bos taurus | 7 | ALA1134018 | assay format | Scientific Literature | |
16. | ALA799734 | Functional | Compound was tested for the inhibition of Rev-RBE RNA complex formation | 10 | ALA1131109 | assay format | Scientific Literature | ||
17. | ALA850161 | ADME | Maximum Frel value for binding to 3'-Fl-AM1A-Rhd in Bacillus subtilis tyr | Bacillus subtilis | 10 | ALA1143547 | nucleic acid format | Scientific Literature | |
18. | ALA999341 | Binding | Activity of Enterococcus APH(3')-3a | Enterococcus | 29 | ALA1140232 | assay format | Scientific Literature | |
19. | ALA999342 | Binding | Ratio of kcat to Km of Enterococcus APH(3')-3a | Enterococcus | 29 | ALA1140232 | assay format | Scientific Literature | |
20. | ALA999343 | Functional | Antibacterial activity against Escherichia coli TG1 pET28a plasmid encoded for APH(3')-3a after 12 to 18 hrs | Escherichia coli | 29 | ALA1140232 | organism-based format | Scientific Literature |