# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA707922 | F | Concentration required for 50% inhibition of cell growth of L1210 leukemic cell lines in mouse. | Mus musculus | 8 | ALA1125887 | cell-based format | Scientific Literature | |
2. | ALA837959 | F | Cytotoxic concentration against bovine viral diarrhea virus (BVDV) in MDBK cells | Bos taurus | 4 | ALA1141159 | cell-based format | Scientific Literature | |
3. | ALA836693 | F | Cytotoxic concentration against HCV replication RNA levels in Huh7 cells determined by HCV replicon assay | Homo sapiens | 4 | ALA1141159 | cell-based format | Scientific Literature | |
4. | ALA833164 | F | Effective concentration required to reduce HCV replication RNA levels in Huh7 cells by 90% determined by HCV replicon assay | Homo sapiens | 4 | ALA1141159 | cell-based format | Scientific Literature | |
5. | ALA833307 | F | Effective concentration required to reduce cytopathic effects caused by bovine viral diarrhea virus (BVDV) in MDBK cells by 90% | Bos taurus | 4 | ALA1141159 | cell-based format | Scientific Literature | |
6. | ALA911146 | P | Aqueous solubility of the compound | 2 | ALA1137330 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA911147 | P | Distribution coefficient, log P of the compound | 2 | ALA1137330 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA911148 | P | Chemical stability at pH 4.5 | 1 | ALA1137330 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA911149 | P | Chemical stability at pH 7.2 | 1 | ALA1137330 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA911178 | A | Protein binding in rat plasma at 20 uM | Rattus norvegicus | 2 | ALA1137330 | cell-free format | Scientific Literature | |
11. | ALA910542 | A | Apparent oral bioavailability in jugular vein cannulated Sprague-Dawley rat at 100 mg/kg, po administered as prodrug | Rattus norvegicus | 1 | ALA1137330 | organism-based format | Scientific Literature | |
12. | ALA910544 | A | Cmax in jugular vein cannulated Sprague-Dawley rat at 100 mg/kg, po administered as prodrug | Rattus norvegicus | 1 | ALA1137330 | organism-based format | Scientific Literature | |
13. | ALA910545 | A | Terminal half life in jugular vein cannulated Sprague-Dawley rat at 100 mg/kg, po administered as prodrug | Rattus norvegicus | 1 | ALA1137330 | organism-based format | Scientific Literature | |
14. | ALA910546 | A | Tmax in jugular vein cannulated Sprague-Dawley rat at 100 mg/kg, po administered as prodrug | Rattus norvegicus | 1 | ALA1137330 | organism-based format | Scientific Literature | |
15. | ALA910547 | A | AUC(0-t) in jugular vein cannulated Sprague-Dawley rat at 100 mg/kg, po administered as prodrug | Rattus norvegicus | 1 | ALA1137330 | organism-based format | Scientific Literature | |
16. | ALA910548 | A | Cmax in Sprague-Dawley rat after 15 days at 60 mg/kg/day, iv | Rattus norvegicus | 1 | ALA1137330 | organism-based format | Scientific Literature | |
17. | ALA910549 | A | AUC in Sprague-Dawley rat after 15 days at 60 mg/kg/day, iv | Rattus norvegicus | 1 | ALA1137330 | organism-based format | Scientific Literature | |
18. | ALA912423 | P | Chemical stability at pH 1.2 | 1 | ALA1137330 | small-molecule physicochemical format | Scientific Literature | ||
19. | ALA910985 | B | Activity of human dCK expressed in HepG2 cells assessed as phosphorylation by coupled enzyme assay | Homo sapiens | 7 | ALA1142170 | cell-based format | Scientific Literature | |
20. | ALA910984 | B | Ratio of Kcat to Km for human dCK expressed in HepG2 cells | Homo sapiens | 7 | ALA1142170 | cell-based format | Scientific Literature |