# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA914451 | B | Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranes | Cavia porcellus | 51 | cell membrane format | Scientific Literature | ||
2. | ALA914453 | B | Displacement of [3H]ketanserin from histamine H2 receptor in human cortex membranes | Homo sapiens | 51 | cell membrane format | Scientific Literature | ||
3. | ALA914455 | B | Displacement of [3H]prazosin from adrenergic alpha-1 receptor in rat brain membranes | Rattus norvegicus | 51 | cell membrane format | Scientific Literature | ||
4. | ALA914457 | F | Inhibition of increase in histamine-induced cutaneous vascular permeability in orally dosed Wistar rat model after 4 hrs | Rattus norvegicus | 36 | organism-based format | Scientific Literature | ||
5. | ALA914458 | F | Inhibition of increase in histamine-induced cutaneous vascular permeability in orally dosed Wistar rat model after 8 hrs | Rattus norvegicus | 18 | organism-based format | Scientific Literature | ||
6. | ALA914460 | F | Ex vivo displacement of [3H]mepyramine from brain histamine H1 receptor in orally dosed Swiss Albino mouse | Mus musculus | 18 | organism-based format | Scientific Literature | ||
7. | ALA914459 | A | Half life in Wistar rat at 1 mg/kg, iv after 8 hrs | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
8. | ALA914461 | A | Volume of distribution at steady state in Wistar rat at 1 mg/kg, iv after 8 hrs | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
9. | ALA914462 | A | Clearance in Wistar rat at 1 mg/kg, iv after 8 hrs | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
10. | ALA914464 | F | Effect on QT interval prolongation in Dunkin-Hartley guinea pigs at 30 mg/kg, iv | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
11. | ALA914466 | A | Inhibition of CYP3A4 in human microsomes at 25 uM | Homo sapiens | 6 | microsome format | Scientific Literature | ||
12. | ALA913855 | F | Inhibition of increase in histamine-induced cutaneous vascular permeability in orally dosed Wistar rat model after 1 hrs | Rattus norvegicus | 6 | organism-based format | Scientific Literature |