# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA914875 | B | Inhibition of human AICAR Tfase | Homo sapiens | 24 | ALA1149296 | single protein format | Scientific Literature | |
2. | ALA977313 | B | Binding affinity to photoactivated rhodopsin in bovine retinal rod outer-segment membranes assessed as induction of extra receptor MII state stabilization by UV/visible difference spectroscopy | Bos taurus | 2 | ALA1140033 | assay format | Scientific Literature | |
3. | ALA977314 | B | Inhibition of bovine retinal rod outer-segment photoactivated rhodopsin-transducer interaction by transducer release assay | Bos taurus | 2 | ALA1140033 | single protein format | Scientific Literature | |
4. | ALA979110 | B | Inhibition of Spirulina platensis adenylyl cyclase assessed as cAMP level by cAMP immunogenic assay | Arthrospira platensis | 6 | ALA1155881 | single protein format | Scientific Literature | |
5. | ALA979111 | B | Inhibition of human recombinant soluble adenylyl cyclase | Homo sapiens | 4 | ALA1155881 | single protein format | Scientific Literature | |
6. | ALA979112 | B | Inhibition of forskolin-stimulated human transmembrane adenylyl cyclase activity in HEK293 cells at 100 uM | Homo sapiens | 2 | ALA1155881 | cell-based format | Scientific Literature | |
7. | ALA979113 | B | Inhibition of forskolin-stimulated adenylyl cyclase 1 activity expressed in HEK293 cells at 100 uM | 2 | ALA1155881 | cell-based format | Scientific Literature | ||
8. | ALA979114 | B | Inhibition of basal activity of adenylyl cyclase 2 expressed in HEK293 cells at 100 uM | 2 | ALA1155881 | cell-based format | Scientific Literature | ||
9. | ALA979115 | B | Inhibition of forskolin-stimulated adenylyl cyclase 5 activity expressed in HEK293 cells at 100 uM | 2 | ALA1155881 | cell-based format | Scientific Literature | ||
10. | ALA979116 | B | Inhibition of basal activity of adenylyl cyclase 9 expressed in HEK293 cells at 100 uM | 2 | ALA1155881 | cell-based format | Scientific Literature | ||
11. | ALA1068068 | B | Inhibition of human tyrosyl-DNA phosphodiesterase 1 after 30 mins by alpha high throughput screening assay | Homo sapiens | 4 | ALA1157706 | single protein format | Scientific Literature | |
12. | ALA1109822 | B | Inhibition of human DNA topoisomerase 1 up to 100 uM | Homo sapiens | 1 | ALA1156254 | single protein format | Scientific Literature | |
13. | ALA1109823 | B | Inhibition of human APE1 up to 100 uM | Homo sapiens | 1 | ALA1156254 | single protein format | Scientific Literature | |
14. | ALA1109824 | B | Inhibition of human Tdp1 expressed in Escherichia coli assessed as blockade of enzyme-mediated hydrolysis of phosphodiester linkage between tyrosine and 3^-end of single stranded N14Y DNA substrate by SDS-PAGE electrophoresis | Homo sapiens | 4 | ALA1156254 | assay format | Scientific Literature | |
15. | ALA1109825 | B | Inhibition of human Tdp1 expressed in Escherichia coli assessed as blockade of enzyme-mediated hydrolysis of phosphodiester linkage between tyrosine and double stranded DNA substrate bearing blunt end by SDS-PAGE electrophoresis | Homo sapiens | 1 | ALA1156254 | assay format | Scientific Literature | |
16. | ALA1109826 | B | Inhibition of human Tdp1 expressed in Escherichia coli assessed as blockade of enzyme-mediated hydrolysis of phosphodiester linkage between tyrosine and double stranded DNA substrate bearing 5^-overhang end by SDS-PAGE electrophoresis | Homo sapiens | 1 | ALA1156254 | assay format | Scientific Literature | |
17. | ALA1109827 | B | Binding affinity to human Tdp1 amine-coupled to sensor chip assessed as increase in resonance units by SPR | Homo sapiens | 2 | ALA1156254 | single protein format | Scientific Literature | |
18. | ALA1109828 | B | Inhibition of human Tdp1 H493R mutant assessed as decrease in enzyme-DNA complexes by DNA sequencing method | Homo sapiens | 1 | ALA1156254 | assay format | Scientific Literature | |
19. | ALA1109829 | B | Inhibition of human Tdp1 H493R mutant assessed as decrease in enzyme-DNA complexes by SDS-PAGE | Homo sapiens | 1 | ALA1156254 | assay format | Scientific Literature | |
20. | ALA1275001 | B | Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coli | 31 | ALA1268807 | assay format | Scientific Literature |