| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA916453 | F | Antiproliferative activity against human A2780 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA1102623 | F | Cytotoxicity against human HT-29 cells at 5 uM after 24 hrs by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA1102624 | A | Cytotoxicity against human CCD-18Co cells at 5 uM after 48 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA1102625 | F | Cytotoxicity against human HCT116 cells at 5 uM after 24 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA1102626 | F | Cytotoxicity against human HT-29 cells after 24 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA1102627 | A | Cytotoxicity against human CCD-18Co cells at 5 uM after 24 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 7. | ALA3124625 | B | Inhibition of INFgamma-induced STAT1 activation in rat INS-1E cells assessed as reduction of STAT1-DNA binding activity at 10 uM preincubated for 30 mins followed by cytokine challenge measured after 60 mins by electrophoretic mobility shift assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3124626 | B | Inhibition of TNFalpha-induced NFkappaB activation in rat INS-1E cells assessed as reduction of NFkappaB-DNA binding activity at 25 uM preincubated for 30 mins followed by cytokine challenge measured after 60 mins by electrophoretic mobility shift assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA3124627 | B | Inhibition of TNFalpha-induced NFkappaB activation in human MDA-MB-231 cells assessed as reduction of NFkappaB-DNA binding activity at 50 uM preincubated for 30 mins followed by cytokine challenge measured after 60 mins by electrophoretic mobility shift assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3124629 | B | Inhibition of INFgamma-induced STAT1 activation in rat INS-1E cells assessed as reduction of STAT1-DNA binding activity at 25 uM preincubated for 30 mins followed by cytokine challenge measured after 60 mins by electrophoretic mobility shift assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3124630 | B | Inhibition of STAT1 in human MDA-MD-231 cells assessed as suppression of INFgamma-induced SOCS-1 expression at 25 to 40 uM by Northern blotting technique | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3124631 | B | Inhibition of INFgamma-induced STAT1 activation in human MDA-MD-231 cells assessed as reduction of STAT1-DNA binding activity at 50 uM preincubated for 30 mins followed by cytokine challenge measured after 60 mins by electrophoretic mobility shift assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA3124633 | B | Inhibition of INFgamma-induced STAT1 activation in human MDA-MD-231 cells assessed as reduction of STAT1-DNA binding activity preincubated for 30 mins followed by cytokine challenge measured after 60 mins by electrophoretic mobility shift assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA3124634 | B | Binding affinity to STAT1 (unknown origin) by surface plasmon resonance assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 15. | ALA3862788 | B | Inhibition of calf thymus DNA polymerase alpha assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as template/primer preincubated for 10 mins followed by template/primer addition measured after 60 mins | Bos taurus | 12 | assay format | Scientific Literature | ||
| 16. | ALA3862789 | B | Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as template/primer preincubated for 10 mins followed by template/primer addition measured after 60 mins | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 17. | ALA3862790 | F | Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 18. | ALA4337973 | B | Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pSG483 DNA at 12.5 to 200 uM after 30 mins by ethidium bromide staining based agarose gel electrophoresis method | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 19. | ALA4337974 | B | Inhibition of human topoisomerase 2beta-mediated relaxation of supercoiled pSG483 DNA at 12.5 to 200 uM after 30 mins by ethidium bromide staining based agarose gel electrophoresis method | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 20. | ALA4337977 | B | Inhibition of human topoisomerase 2alpha-mediated DNA cleavage at 12.5 to 200 uM using supercoiled pSG483 as substrate after 30 mins by ethidium bromide staining based gel electrophoresis method | Homo sapiens | 4 | single protein format | Scientific Literature |
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