# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA914524 | B | Inhibition of human DHFR | Homo sapiens | 6 | single protein format | Scientific Literature | ||
2. | ALA914525 | B | Inhibition of Escherichia coli DHFR | Escherichia coli | 6 | single protein format | Scientific Literature | ||
3. | ALA914522 | B | Inhibition of Toxoplasma gondii DHFR | Toxoplasma gondii | 6 | single protein format | Scientific Literature | ||
4. | ALA914523 | B | Inhibition of human thymidylate synthase | Homo sapiens | 6 | single protein format | Scientific Literature | ||
5. | ALA914520 | B | Inhibition of Escherichia coli thymidylate synthase | Escherichia coli | 6 | single protein format | Scientific Literature | ||
6. | ALA914521 | B | Inhibition of Toxoplasma gondii thymidylate synthase | Toxoplasma gondii | 6 | single protein format | Scientific Literature | ||
7. | ALA914518 | F | Growth inhibition of human CCRF-CEM cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA914516 | F | Growth inhibition of methotrexate-resistant human CCRF-CEM R1 cells overproducing DHFR after 120 hrs | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA914517 | F | Growth inhibition of methotrexate-transport-resistant human CCRF-CEM R2 cells after 120 hrs | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
10. | ALA914515 | F | Growth inhibition of methotrexate-resistant human CCRF-CEM R30dm cells expressing low levels of folyl-poly-glutamate synthetase after 120 hrs | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA914513 | B | Activity of human recombinant cytosolic FPGS | Homo sapiens | 3 | single protein format | Scientific Literature | ||
12. | ALA914514 | B | Activity of human recombinant cytosolic FPGS relative to aminopterin | Homo sapiens | 3 | single protein format | Scientific Literature | ||
13. | ALA914511 | B | Ratio of Vmax relative to amphotericin to Km of human recombinant cytosolic FPGS | Homo sapiens | 3 | single protein format | Scientific Literature | ||
14. | ALA914512 | F | Protection of drug-induced growth inhibition by 0.1 uM leucovorin in human CCRF-CEM cells assessed as growth at 1000 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA914509 | F | Protection of drug-induced growth inhibition by 1 uM leucovorin in human CCRF-CEM cells assessed as growth at 1000 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA914507 | F | Protection of drug-induced growth inhibition by 10 uM leucovorin in human CCRF-CEM cells assessed as growth at 1000 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA904361 | F | Cell growth in human CCRF-CEM cells at 1000 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA904355 | F | Cell growth in human CCRF-CEM cells at 4000 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA904353 | A | Cytotoxicity against human CCRF-CEM cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA904354 | A | Cytotoxicity against human HL60 cells | Homo sapiens | 1 | cell-based format | Scientific Literature |