# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA913064 | B | Binding affinity at Beta-lactamase SHV1 expressed in Escherichia coli DH10B cells | Escherichia coli | 3 | ALA1146195 | cell-based format | Scientific Literature | |
2. | ALA912017 | B | Binding affinity at Beta-lactamase SHV2 G238S expressed in Escherichia coli DH10B cells | Escherichia coli | 3 | ALA1146195 | cell-based format | Scientific Literature | |
3. | ALA914658 | B | Binding affinity at Beta-lactamase SHV5 expressed in Escherichia coli DH10B cells | Escherichia coli | 3 | ALA1146195 | cell-based format | Scientific Literature | |
4. | ALA914659 | B | Binding affinity at Beta-lactamase D104K expressed in Escherichia coli DH10B cells | Escherichia coli | 3 | ALA1146195 | cell-based format | Scientific Literature | |
5. | ALA914660 | B | Binding affinity at Beta-lactamase D104K G238S expressed in Escherichia coli DH10B cells | Escherichia coli | 3 | ALA1146195 | cell-based format | Scientific Literature | |
6. | ALA929722 | B | Inhibition of AmpC beta lactamase | 7 | ALA1141578 | assay format | Scientific Literature | ||
7. | ALA1285311 | B | Inhibition of AmpC beta-lactamase | 16 | ALA1275363 | assay format | Scientific Literature | ||
8. | ALA2039461 | B | Inhibition of Actinomadura sp. R39 PBP using S2d as substrate assessed as residual activity at 1 mM incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Actinomadura sp. R39 | 20 | ALA2034818 | single protein format | Scientific Literature | |
9. | ALA2039464 | B | Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate assessed as residual activity at 1 mM incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Streptococcus pneumoniae R6 | 18 | ALA2034818 | single protein format | Scientific Literature | |
10. | ALA2039471 | B | Inhibition of Streptococcus pneumoniae PBP1b using PATP thioester as substrate assessed as residual activity at 1 mM incubated for 60 mins prior to substrate addition by DNTB-based spectrophotometry in the presence of triton X 100 | Streptococcus pneumoniae | 3 | ALA2034818 | assay format | Scientific Literature | |
11. | ALA2039473 | B | Inhibition of penicillin-resistant Staphylococcus aureus PBP2a assessed as residual activity at 1 mM incubated for 60 mins prior to prior to fluoresceyl-ampicillin labelling measured after 20 mins by SDS-PAGE analysis | Staphylococcus aureus | 20 | ALA2034818 | assay format | Scientific Literature | |
12. | ALA2039474 | B | Inhibition of penicillin-resistant Enterococcus faecium PBP5fm assessed as residual activity at 1 mM incubated for 60 mins prior to prior to fluoresceyl-ampicillin labelling measured after 20 mins by SDS-PAGE analysis | Enterococcus faecium | 20 | ALA2034818 | assay format | Scientific Literature | |
13. | ALA2039475 | B | Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2x using S2d as substrate assessed as residual activity at 1 mM incubated for 4 hrs prior to substrate addition by DNTB-based spectrophotometry | Streptococcus pneumoniae | 12 | ALA2034818 | single protein format | Scientific Literature | |
14. | ALA3391167 | B | Inhibition of beta-lactamase SHV-1 (unknown origin) expressed in Escherichia coli DH10B using nitrocefin as substrate | Not specified | 1 | ALA3390847 | assay format | Scientific Literature | |
15. | ALA3391168 | B | Inhibition of beta-lactamase SHV-1 D104K/G238S mutant (unknown origin) expressed in Escherichia coli DH10B using nitrocefin as substrate | Not specified | 1 | ALA3390847 | assay format | Scientific Literature |