| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA905370 | B | Inhibition of phospholipase B activity of PLB1 in Cryptococcus neoformans var. grubii H99 assessed as loss of 1,2-di[1-14C]palmitoyl phosphatidylcholine at 250 uM | Cryptococcus neoformans var. grubii | 5 | single protein format | Scientific Literature | ||
| 2. | ALA905382 | F | Antifungal activity against Cryptococcus neoformans ATCC 90112 | Cryptococcus neoformans | 17 | organism-based format | Scientific Literature | ||
| 3. | ALA905383 | F | Antifungal activity against Candida albicans ATCC 10231 | Candida albicans | 17 | organism-based format | Scientific Literature | ||
| 4. | ALA905392 | A | Cytotoxicity against human erythrocytes assessed as hemolytic activity at 500 uM | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 5. | ALA3227786 | B | Inhibition of CHKA in human HCT116 cells assessed as [3H]phosphocholine formation using [3H]choline chloride as substrate at 2.4 +/-1 uM incubated for 1 hr prior to substrate addition measured after 1 hr by scintillation counting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3227787 | B | Inhibition of CHKA in human HCT116 cells assessed as [3H]phosphocholine formation using [3H]choline chloride as substrate at 6.5 +/-4 uM incubated for 1 hr prior to substrate addition measured after 1 hr by scintillation counting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA3227788 | F | Growth inhibition of human A549 cells overexpressing CHKA2 after 72 hrs by sulforhodamine assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 8. | ALA3227789 | B | Inhibition of CHKA in human HCT116 cells assessed as [3H]phosphocholine formation using [3H]choline chloride as substrate incubated for 1 hr prior to substrate addition measured after 1 hr by scintillation counting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA3227790 | F | Growth inhibition of human HCT116 cells overexpressing CHKA2 after 72 hrs by sulforhodamine assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 10. | ALA3227792 | B | Competitive inhibition of recombinant delta49N CHKA2 (unknown origin) using 72 uM choline as substrate by Lineweaver-burk plot analysis in presence of 10 uM to 5 mM ATP | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA3227793 | B | Competitive inhibition of recombinant delta49N CHKA2 (unknown origin) using 40 uM to 20 mM choline as substrate by Lineweaver-burk plot analysis in presence of 450 uM ATP | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA3227794 | B | Inhibition of recombinant delta49N CHKA2 (unknown origin) assessed as ADP formation using choline as substrate by enzyme coupled assay | Homo sapiens | 11 | assay format | Scientific Literature |
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