# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3620069 | Binding | Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by colorimetric assay | Homo sapiens | 37 | ALA3616389 | assay format | Scientific Literature | |
2. | ALA3620070 | Binding | Inhibition of human recombinant DAO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by colorimetric assay | Homo sapiens | 37 | ALA3616389 | assay format | Scientific Literature | |
3. | ALA3813191 | ADME | Cytotoxicity against mouse RAW264.7 cells assessed as survival rate at 2.5 uM after 24 hrs by MTT assay | Mus musculus | 56 | ALA3808275 | cell-based format | Scientific Literature | |
4. | ALA3813192 | ADME | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Mus musculus | 56 | ALA3808275 | cell-based format | Scientific Literature | |
5. | ALA3813193 | ADME | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 5 uM after 24 hrs by MTT assay | Mus musculus | 56 | ALA3808275 | cell-based format | Scientific Literature | |
6. | ALA3813195 | Functional | Inhibition of RANKL-induced osteoclast differentiation in mouse RAW264.7 cells assessed as TRAP-positive multinucleated cells level at 2.5 uM incubated with compound in presence of RANKL for 4 days by TRAP staining based light microscopic analysis relative to RANKL alone | Mus musculus | 56 | ALA3808275 | cell-based format | Scientific Literature | |
7. | ALA905766 | Binding | Inhibition of PTP1B | 24 | ALA1143766 | single protein format | Scientific Literature | ||
8. | ALA1664428 | Binding | Inhibition of mushroom tyrosinase at 1 mM after 10 mins | Agaricus bisporus | 94 | ALA1649420 | single protein format | Scientific Literature | |
9. | ALA1664429 | Binding | Inhibition of human recombinant 5-lipoxygenase at 1 mM after 10 mins by fluorescence assay | Homo sapiens | 89 | ALA1649420 | single protein format | Scientific Literature | |
10. | ALA1664430 | Binding | Inhibition of recombinant anthrax lethal factor at 1 mM after 30 mins by fluorescence assay | Bacillus anthracis | 93 | ALA1649420 | single protein format | Scientific Literature | |
11. | ALA1664431 | Binding | Inhibition of human recombinant MMP1 at 1 mM after 30 mins | Homo sapiens | 96 | ALA1649420 | single protein format | Scientific Literature | |
12. | ALA1664432 | Binding | Inhibition of human recombinant MMP2 at 1 mM after 30 mins | Homo sapiens | 96 | ALA1649420 | single protein format | Scientific Literature | |
13. | ALA1664433 | Binding | Inhibition of human recombinant MMP3 at 1 mM after 30 mins | Homo sapiens | 96 | ALA1649420 | single protein format | Scientific Literature | |
14. | ALA1664434 | Binding | Inhibition of human recombinant MMP8 at 1 mM after 30 mins | Homo sapiens | 96 | ALA1649420 | single protein format | Scientific Literature | |
15. | ALA1664435 | Binding | Inhibition of human recombinant MMP9 at 1 mM after 30 mins | Homo sapiens | 96 | ALA1649420 | single protein format | Scientific Literature | |
16. | ALA1664436 | Binding | Inhibition of mouse recombinant iNOS at 1 mM after 40 mins by colorimetric assay | Mus musculus | 74 | ALA1649420 | single protein format | Scientific Literature | |
17. | ALA3097527 | Binding | Inhibition of recombinant human IDO1 expressed in Escherichia coli EC538 using L-tryptophan as substrate at 1 mM after 1 hr relative to control | Homo sapiens | 59 | ALA3091438 | assay format | Scientific Literature | |
18. | ALA3252206 | Functional | Antiinflammatory activity against carrageenan-induced foot edema in rat administered via gastric gavage | Rattus norvegicus | 29 | ALA3244301 | organism-based format | Scientific Literature |