# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA904107 | T | CNS toxicity in iv dosed Sprague-Dawley rat assessed as cumulative convulsion dose | Rattus norvegicus | 52 | organism-based format | Scientific Literature | ||
2. | ALA904109 | F | Antiarrhythmic activity in intravenously dosed Sprague-Dawley rat with ischemia-induced arrhythmia | Rattus norvegicus | 43 | organism-based format | Scientific Literature | ||
3. | ALA905103 | F | Effect on blood pressure in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% change in arterial blood pressure | Rattus norvegicus | 25 | organism-based format | Scientific Literature | ||
4. | ALA905104 | F | Effect on ECG parameters in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% prolongation of P-R interval | Rattus norvegicus | 23 | organism-based format | Scientific Literature | ||
5. | ALA905105 | F | Effect on ECG parameters in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% lengthening in QT1 interval | Rattus norvegicus | 25 | organism-based format | Scientific Literature | ||
6. | ALA905106 | F | Effect on ECG parameters in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% lengthening in QT2 interval | Rattus norvegicus | 26 | organism-based format | Scientific Literature | ||
7. | ALA905107 | F | Effect on electrical stimulation in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% prolongation of in current threshold for induction of extrasystole | Rattus norvegicus | 27 | organism-based format | Scientific Literature | ||
8. | ALA905108 | F | Effect on electrical stimulation in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% increase in effective refractory period | Rattus norvegicus | 27 | organism-based format | Scientific Literature | ||
9. | ALA905109 | T | Toxicity in intravenously dosed CD1 mouse | Mus musculus | 27 | organism-based format | Scientific Literature | ||
10. | ALA905110 | B | Inhibition of human heart sodium channel Nav1.5 by patch-clamp method | Homo sapiens | 7 | single protein format | Scientific Literature | ||
11. | ALA905111 | B | Inhibition of human potassium channel Kv1.5 by patch-clamp method | Homo sapiens | 7 | single protein format | Scientific Literature | ||
12. | ALA905112 | B | Inhibition of rat potassium channel Kv4.2 by patch-clamp method | Rattus norvegicus | 7 | single protein format | Scientific Literature | ||
13. | ALA905113 | B | Inhibition of rat potassium channel Kv2.1 by patch-clamp method | Rattus norvegicus | 7 | single protein format | Scientific Literature | ||
14. | ALA905116 | F | Effect on Mongrel dog sterile pericarditis atrial fibrillation model assessed as conversion of atrial fibrillation to normal sinus rhythm | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
15. | ALA905117 | F | Effect on Mongrel dog sterile pericarditis atrial fibrillation model assessed as dose for conversion of atrial fibrillation to normal sinus rhythm | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
16. | ALA905118 | A | Half life in Wistar rat at 12 mg/kg. iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
17. | ALA905120 | A | Volume of distribution at steady state in Wistar rat at 12 mg/kg. iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
18. | ALA905122 | A | Clearance in Wistar rat at 12 mg/kg. iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
19. | ALA905124 | A | Oral bioavailability in Wistar rat at 24 mg/kg. iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
20. | ALA905126 | F | Reduction of blood pressure in Mongrel dog vagal atrial fibrillation model | Canis lupus familiaris | 3 | organism-based format | Scientific Literature |